探索用于治疗的碳水化合物：未来方向综述

Wang Jie, Zhang Yukun, Lu Qi, Xing Dongming, Zhang Renshuai

The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, China.

Cancer Institute, Qingdao University, Qingdao, China.

Front Pharmacol. 2021 Nov 16;12:756724. doi: 10.3389/fphar.2021.756724. eCollection 2021.

Carbohydrates are important components of foods and essential biomolecules performing various biological functions in living systems. A variety of biological activities besides providing fuel have been explored and reported for carbohydrates. Some carbohydrates have been approved for the treatment of various diseases; however, carbohydrate-containing drugs represent only a small portion of all of the drugs on the market. This review summarizes several potential development directions of carbohydrate-containing therapeutics, with the hope of promoting the application of carbohydrates in drug development.

碳水化合物是食物的重要组成部分，也是在生物系统中执行各种生物学功能的必需生物分子。除了提供能量外，人们还探索并报道了碳水化合物的多种生物活性。一些碳水化合物已被批准用于治疗各种疾病；然而，含碳水化合物的药物仅占市场上所有药物的一小部分。本综述总结了含碳水化合物疗法的几个潜在发展方向，希望能促进碳水化合物在药物开发中的应用。