Milner James, Gonçalves Francisco, Gonçalves Lino
Cardiology Department, Centro Hospitalar e Universitário de Coimbra.
Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
J Cardiol Cases. 2021 May 15;24(5):244-246. doi: 10.1016/j.jccase.2021.04.005. eCollection 2021 Nov.
The development of malignant neoplasms over the site of pacemaker implantation is a rare event, with a limited number of published case reports. We report the case of a 78-year-old male who presented with discomfort and pocket mass expansion, reportedly following trauma. Due to initial presumption of a simple hematoma, dissection and drainage were performed without tissue collection for histology. Later presentation with an exophytic ulcerated mass led to biopsy and identification of a lymphoplasmacytic lymphoma. To the best of our knowledge this is the first reported case of a cutaneous lymphoplasmacytic lymphoma presenting as a pacemaker pocket mass, and underlines the importance of systematic pacemaker inspection, of adequate histological characterization and of a high degree of clinical suspicion for the identification malignancy in this context. < We report the first case of a lymphoplasmacytic lymphoma presenting primarily as a pacemaker pocket mass. Lymphoplasmacytic lymphoma is a rare and indolent subtype of Non-Hodgkin lymphoma that may present with cutaneous manifestations. Due to the extreme rarity of malignant neoplasms presenting as pacemaker pocket masses, a high degree is clinical suspicion is required, and tissue histology plays a key role in the diagnosis.>.
起搏器植入部位发生恶性肿瘤是一种罕见事件,仅有数量有限的病例报告发表。我们报告一例78岁男性患者,据报道其在经历创伤后出现不适及起搏器囊袋肿物增大。由于最初推测为单纯血肿,因此在未采集组织进行组织学检查的情况下进行了切开引流。后来出现的外生性溃疡肿物导致进行活检,并确诊为淋巴浆细胞性淋巴瘤。据我们所知,这是首例报告的以起搏器囊袋肿物形式出现的皮肤淋巴浆细胞性淋巴瘤病例,强调了在此情况下系统检查起搏器、进行充分组织学特征分析以及保持高度临床怀疑以识别恶性肿瘤的重要性。<我们报告首例主要表现为起搏器囊袋肿物的淋巴浆细胞性淋巴瘤病例。淋巴浆细胞性淋巴瘤是非霍奇金淋巴瘤的一种罕见且惰性的亚型,可能出现皮肤表现。由于以起搏器囊袋肿物形式出现的恶性肿瘤极为罕见,因此需要高度临床怀疑,且组织学检查在诊断中起关键作用。>