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一项针对多发性硬化症疲劳的两组教育项目的多中心随机对照试验:在一个地点进行的长期(5 - 6年)随访。

A multisite randomized controlled trial of two group education programs for fatigue in multiple sclerosis: Very long term (5-6 year) follow-up at one site.

作者信息

Norton Julia, Joos Sandra, Cameron Michelle H, Hugos Cinda L

出版信息

Mult Scler J Exp Transl Clin. 2021 Nov 25;7(4):20552173211054454. doi: 10.1177/20552173211054454. eCollection 2021 Oct.

DOI:10.1177/20552173211054454
PMID:34868627
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8637710/
Abstract

BACKGROUND

A multicomponent group MS fatigue self-management program reduced fatigue impact compared to a rigorous control 12 months after enrollment.

OBJECTIVES

Assess and compare changes between groups in fatigue impact and behavior changes implemented 5-6 years after enrollment.

METHODS

The Modified Fatigue Impact Scale (MFIS) and a behavior change questionnaire were administered 5-6 years after enrollment.

RESULTS

There were no significant changes in mean MFIS scores within or between groups from baseline to 5-6 years later. Behavior changes were of similar frequency in both groups.

CONCLUSION

Fatigue impact was stable and behavior changes were similar between groups 5-6 years after a fatigue self-management program.

摘要

背景

与严格的对照组相比,一项多成分团体MS疲劳自我管理计划在入组12个月后减轻了疲劳影响。

目的

评估并比较入组5 - 6年后两组在疲劳影响和行为改变方面的变化。

方法

在入组5 - 6年后使用改良疲劳影响量表(MFIS)和一份行为改变问卷进行评估。

结果

从基线到5 - 6年后,组内和组间的平均MFIS分数均无显著变化。两组的行为改变频率相似。

结论

在疲劳自我管理计划实施5 - 6年后,疲劳影响稳定,两组间行为改变相似。

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本文引用的文献

1
Pathophysiological and cognitive mechanisms of fatigue in multiple sclerosis.多发性硬化症疲劳的病理生理和认知机制。
J Neurol Neurosurg Psychiatry. 2019 Jun;90(6):642-651. doi: 10.1136/jnnp-2018-320050. Epub 2019 Jan 25.
2
A multicenter randomized controlled trial of two group education programs for fatigue in multiple sclerosis: Long-term (12-month) follow-up at one site.多中心随机对照试验对两种多发性硬化疲劳团体教育方案:长期(12 个月)随访一个地点。
Mult Scler. 2019 May;25(6):871-875. doi: 10.1177/1352458518775920. Epub 2018 May 15.
3
A multicenter randomized controlled trial of two group education programs for fatigue in multiple sclerosis: Short- and medium-term benefits.一项多中心随机对照试验,比较两种多发性硬化疲劳管理团体教育方案的疗效:短期和中期获益。
Mult Scler. 2019 Feb;25(2):275-285. doi: 10.1177/1352458517745723. Epub 2017 Dec 11.
4
A 9-year follow-up of a self-management group intervention for persistent neck pain in primary health care: a randomized controlled trial.初级卫生保健中针对持续性颈部疼痛的自我管理小组干预的9年随访:一项随机对照试验。
J Pain Res. 2016 Dec 30;10:53-64. doi: 10.2147/JPR.S125074. eCollection 2017.
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Health-related quality of life outcomes at 1 and 5 years after a residential retreat promoting lifestyle modification for people with multiple sclerosis.多发性硬化症患者生活方式改变促进疗养后 1 年和 5 年的健康相关生活质量结果。
Neurol Sci. 2013 Feb;34(2):187-95. doi: 10.1007/s10072-012-0982-4. Epub 2012 Feb 25.
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Fatigue characteristics in multiple sclerosis: the North American Research Committee on Multiple Sclerosis (NARCOMS) survey.多发性硬化症的疲劳特征:北美多发性硬化症研究委员会(NARCOMS)调查
Health Qual Life Outcomes. 2008 Nov 14;6:100. doi: 10.1186/1477-7525-6-100.