Nayımoğlu Mehmet, Sarıfakıoğlu Banu, Ustaömer Kübra, Akgül Murat, Isal Arslan Ayşegül
Department of Physical Medicine and Rehabilitation, Namık Kemal University, School of Medicine, Tekirdağ, Turkey.
Department of Urology, Namık Kemal University, School of Medicine, Tekirdağ, Turkey.
Turk J Phys Med Rehabil. 2021 Sep 1;67(3):374-377. doi: 10.5606/tftrd.2021.5135. eCollection 2021 Sep.
Infliximab is an inhibitory of tumor necrosis factor-alpha which is used successfully for the treatment of inflammatory bowel disease and rheumatic disease. It has various side effects including injection-induced reactions, immunosuppression, demyelinating diseases, and cardiac effects. One of the most serious side effects is tuberculosis. In particular, the immunosuppressant drugs have a high risk of reactivating latent tuberculosis infection. Its activation probably may occur as an extra-pulmonary and, occasionally, may result in an unusual infection. Herein, we report a 30-year-old male case treated with infliximab and suffered from isolated testicular tuberculosis.
英夫利昔单抗是一种肿瘤坏死因子-α抑制剂，已成功用于治疗炎症性肠病和风湿性疾病。它有多种副作用，包括注射引起的反应、免疫抑制、脱髓鞘疾病和心脏影响。最严重的副作用之一是结核病。特别是，免疫抑制药物有很高的重新激活潜伏性结核感染的风险。其激活可能发生在肺外，偶尔可能导致不寻常的感染。在此，我们报告一例30岁男性病例，该患者接受英夫利昔单抗治疗后患上孤立性睾丸结核。
