Moyón Miguel Ángel, Añazco Johan Stephany, Vásconez Alex Enrique, Larreategui David, Torres María Belén, Moyón Natali, Borja Tatiana, Molina Gabriel Alejandro
Department of General Surgery, Clínica Pasteur & School of Medicine, Pontificia Universidad Católica del Ecuador (PUCE), Av. Eloy Alfaro, N29-248, Quito 170515, Ecuador.
Department of General Surgery, Clínica Pasteur, Av. Eloy Alfaro, N29-248, Quito 170515, Ecuador.
J Surg Case Rep. 2025 Jun 16;2025(6):rjaf422. doi: 10.1093/jscr/rjaf422. eCollection 2025 Jun.
Ankylosing spondylitis is a chronic inflammatory spondyloarthropathy that will cause severe symptoms and complications if left untreated. Anti-TNF-α inhibitor is the treatment of choice, yet all treatments have difficulties, and opportunistic infections following this therapy are well known. Reactivation of latent tuberculosis (TB) and abdominal TB is a serious problem in this therapy since diagnosis is difficult, as symptoms are nonspecific, and complications can be fatal. We present the case of a 47-year-old female doctor with a past medical history of ankylosing spondylitis; she was treated with infliximab. She began developing abdominal pain that led to an acute abdomen due to abdominal TB. After successful treatment, she fully recovered, and the patient is doing well in follow-ups.
强直性脊柱炎是一种慢性炎症性脊柱关节病,若不治疗会导致严重症状及并发症。抗TNF-α抑制剂是首选治疗方法,但所有治疗都存在困难,且这种治疗后机会性感染是众所周知的。潜伏性结核(TB)和腹部结核的再激活是该治疗中的一个严重问题,因为诊断困难,症状不具特异性,且并发症可能致命。我们报告一例47岁女性医生的病例,她有强直性脊柱炎病史,接受了英夫利昔单抗治疗。她开始出现腹痛,最终因腹部结核导致急腹症。成功治疗后,她完全康复,且患者在随访中情况良好。