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具有过氧化物酶样活性和光电响应的 AgCu@CuO 气凝胶用于灵敏的生物传感。

AgCu@CuO aerogels with peroxidase-like activities and photoelectric responses for sensitive biosensing.

机构信息

Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China.

School of Electronic and Information Engineering, Jingchu University of Technology, Jingmen, 448000, P. R. China.

出版信息

Chem Commun (Camb). 2021 Dec 16;57(100):13788-13791. doi: 10.1039/d1cc06177a.

DOI:10.1039/d1cc06177a
PMID:34870654
Abstract

Photoelectrochemical (PEC) enzymatic biosensors integrate the excellent selectivity of enzymes and high sensitivity of PEC bioanalysis, but the drawbacks such as high cost, poor stability, and tedious immobilization of natural enzymes on photoelectrodes severely suppress their applications. AgCu@CuO aerogel-based photoelectrode materials with both remarkable enzyme-like activities and outstanding photoelectric properties were innovatively designed and synthesized to evaluate the activity of xanthine oxidase with a wide linear detection range and a low limit of detection.

摘要

光电化学(PEC)酶生物传感器将酶的优异选择性和 PEC 生物分析的高灵敏度结合在一起,但天然酶在光电极上的高成本、较差的稳定性和繁琐的固定化等缺点严重抑制了它们的应用。创新性地设计和合成了具有显著类酶活性和优异光电性能的 AgCu@CuO 气凝胶基光电电极材料,以评估黄嘌呤氧化酶的活性,具有较宽的线性检测范围和较低的检测限。

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