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重症监护病房急性心房颤动的管理:一项国际调查。

Management of acute atrial fibrillation in the intensive care unit: An international survey.

机构信息

Department of Intensive Care, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.

Department of Cardiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.

出版信息

Acta Anaesthesiol Scand. 2022 Mar;66(3):375-385. doi: 10.1111/aas.14007. Epub 2021 Dec 14.

DOI:10.1111/aas.14007
PMID:34870855
Abstract

BACKGROUND

Atrial fibrillation (AF) is common in intensive care unit (ICU) patients and is associated with poor outcomes. Different management strategies exist, but the evidence is limited and derived from non-ICU patients. This international survey of ICU doctors evaluated the preferred management of acute AF in ICU patients.

METHOD

We conducted an international online survey of ICU doctors with 27 questions about the preferred management of acute AF in the ICU, including antiarrhythmic therapy in hemodynamically stable and unstable patients and use of anticoagulant therapy.

RESULTS

A total of 910 respondents from 70 ICUs in 14 countries participated in the survey with 24%-100% of doctors from sites responding. Most ICUs (80%) did not have a local guideline for the management of acute AF. The preferred first-line strategy for the management of hemodynamically stable patients with acute AF was observation (95% of respondents), rhythm control (3%), or rate control (2%). For hemodynamically unstable patients, the preferred strategy was observation (48%), rhythm control (48%), or rate control (4%). Overall, preferred antiarrhythmic interventions included amiodarone, direct current cardioversion, beta-blockers other than sotalol, and magnesium in that order. A total of 67% preferred using anticoagulant therapy in ICU patients with AF, among whom 61% preferred therapeutic dose anticoagulants and 39% prophylactic dose anticoagulants.

CONCLUSION

This international survey indicated considerable practice variation among ICU doctors in the clinical management of acute AF, including the overall management strategies and the use of antiarrhythmic interventions and anticoagulants.

摘要

背景

心房颤动(AF)在重症监护病房(ICU)患者中很常见,与不良预后相关。存在不同的管理策略,但证据有限,且源自非 ICU 患者。这项针对 ICU 医生的国际调查评估了 ICU 患者急性 AF 的首选管理方法。

方法

我们对 ICU 医生进行了一项国际在线调查,共 27 个问题涉及 ICU 患者急性 AF 的首选管理方法,包括血流动力学稳定和不稳定患者的抗心律失常治疗以及抗凝治疗的应用。

结果

共有来自 14 个国家的 70 个 ICU 的 910 名医生参与了这项调查,每个站点的医生参与率为 24%-100%。大多数 ICU(80%)没有急性 AF 管理的当地指南。血流动力学稳定的急性 AF 患者的首选一线治疗策略是观察(95%的受访者)、节律控制(3%)或心率控制(2%)。对于血流动力学不稳定的患者,首选策略是观察(48%)、节律控制(48%)或心率控制(4%)。总的来说,首选的抗心律失常干预措施包括胺碘酮、直流电复律、索他洛尔以外的β受体阻滞剂和镁。共有 67%的受访者倾向于在 ICU 伴有 AF 的患者中使用抗凝治疗,其中 61%倾向于使用治疗剂量抗凝剂,39%倾向于使用预防剂量抗凝剂。

结论

这项国际调查表明,ICU 医生在急性 AF 的临床管理方面存在相当大的实践差异,包括整体管理策略以及抗心律失常干预和抗凝剂的使用。

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