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伴有危急 COVID-19 的血液透析患者的特征。

Characteristics of hemodialysis patient with critical COVID-19.

机构信息

Department of Clinical Engineering, Faculty of Human Care at Makuhari, Tohto University, Chiba, Japan.

Department of Nephrology, Sangenjaya Hospital, Tokyo, Japan.

出版信息

Ther Apher Dial. 2022 Oct;26(5):969-976. doi: 10.1111/1744-9987.13773. Epub 2021 Dec 14.

Abstract

INTRODUCTION

The clinical course of hemodialysis patients with COVID-19 still remains unclear.

METHODS

Thirty-four hemodialysis patients were retrospectively enrolled. Patients were divided according to disease severity, and clinical symptoms and laboratory data at admission were compared.

RESULTS

The serum C-reactive protein (CRP) level, d-dimer level, and white blood cell (WBC) count were significantly higher in the group with critical disease than in the group with mild to severe disease (p = 0.005, p = 0.039, and p = 0.045). The serum CRP level exceeded 10 mg/dl within 7 days of clinical onset in all the cases with critical disease.

CONCLUSION

Hemodialysis patients with COVID-19 who have elevated serum CRP and d-dimer levels, and an elevated WBC count at admission and patients with serum CRP levels exceeding 10 mg/dl before day 7 after clinical onset should be carefully monitored for possible progression to critical disease.

摘要

简介

COVID-19 血液透析患者的临床病程仍不清楚。

方法

回顾性纳入 34 名血液透析患者。根据疾病严重程度进行分组,并比较入院时的临床症状和实验室数据。

结果

重症组患者的血清 C 反应蛋白(CRP)、D-二聚体和白细胞(WBC)计数均明显高于轻症至重症组(p=0.005,p=0.039 和 p=0.045)。所有重症患者在临床发病后 7 天内血清 CRP 均超过 10mg/dl。

结论

入院时血清 CRP、D-二聚体水平升高,WBC 计数升高,且临床发病后第 7 天前血清 CRP 水平超过 10mg/dl 的 COVID-19 血液透析患者,应密切监测其病情进展为重症的可能。

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