Frank G, Beyer J
Xenobiotica. 1986 Apr;16(4):291-4. doi: 10.3109/00498258609043531.
Frogs injected with 3-nitrophenol excreted 85-93% of the administered dose within 17 h; 70-90% dose was metabolized. Metabolites identified comprise 3-nitrophenyl glucuronide (57% dose), 3-nitrophenyl sulphate (24% dose), and 3-acetamidophenyl sulphate (2% dose). Traces of the following metabolites were found: 3-acetamidophenyl glucuronide, 3-acetamidophenol, 4-nitrocatechol, nitroquinol, 4-nitrocatechol sulphate and nitroquinol sulphate.
注射3-硝基苯酚的青蛙在17小时内排出了85-93%的给药剂量;70-90%的剂量被代谢。鉴定出的代谢产物包括3-硝基苯基葡萄糖醛酸苷(占剂量的57%)、3-硝基苯基硫酸盐(占剂量的24%)和3-乙酰氨基苯基硫酸盐(占剂量的2%)。还发现了以下代谢产物的痕量:3-乙酰氨基苯基葡萄糖醛酸苷、3-乙酰氨基酚、4-硝基儿茶酚、硝基喹啉、4-硝基儿茶酚硫酸盐和硝基喹啉硫酸盐。