Hydroxylation and conjugation of phenol by the frog Rana temporaria.

Frogs injected with phenol excrete 67-95% of dose in 15 h; 32-87% of dose are metabolites. Metabolites identified were phenyl sulphate (15-44% of dose), phenyl glucuronide (10-25% of dose), catechol sulphate (up to 7% of dose), quinol sulphate (1-25% of dose), resorcinol and catechol (traces).