Mitchell M D, Kundel H L, Steinberg M E, Kressel H Y, Alavi A, Axel L
AJR Am J Roentgenol. 1986 Jul;147(1):67-71. doi: 10.2214/ajr.147.1.67.
The capabilities of MRI, radionuclide bone scanning, and X-ray CT in diagnosing avascular necrosis of the hip were compared in a controlled statistical study. Diagnostic ability was measured as the area under the receiver-operating-characteristic curve. Differences in efficacy among various case pools and the standard errors of those differences were calculated. MR was better than both other techniques over the entire case pool, with the difference between MR and radionuclide scanning exceeding 2 standard errors (p less than 0.01). In the subsample of patients including more early cases, MR was better than CT by greater than 2 standard errors and better than radionuclide scanning by over 3 standard errors. This is evidence that MR is the most sensitive imaging technique for the early diagnosis of avascular necrosis.
在一项对照统计研究中，对磁共振成像（MRI）、放射性核素骨扫描和X射线计算机断层扫描（X-ray CT）诊断髋关节缺血性坏死的能力进行了比较。诊断能力通过受试者操作特征曲线下面积来衡量。计算了不同病例组之间疗效的差异以及这些差异的标准误差。在整个病例组中，磁共振成像比其他两种技术都要好，磁共振成像与放射性核素扫描之间的差异超过2个标准误差（p小于0.01）。在包括更多早期病例的患者亚组中，磁共振成像比计算机断层扫描好超过2个标准误差，比放射性核素扫描好超过3个标准误差。这证明磁共振成像是早期诊断缺血性坏死最敏感的成像技术。
