Foo Chuan T, Paterson Anna, Duckworth Adam, Herre Jurgen
Department of Respiratory Medicine, Cambridge University Hospitals NHS Foundation Trust, Cambridge, England.
Department of Histopathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, England.
Chest. 2021 Dec;160(6):e609-e611. doi: 10.1016/j.chest.2021.07.031.
Malignant pleural effusion is common in mesothelioma. We report a case of viscous recurrent malignant mesothelioma pleural effusion. The viscosity was due to the presence of hyaluronic acid and resulted in prolonged drainage time. The use of intrapleural hyaluronidase significantly reduced fluid viscosity and drainage duration. No adverse reactions were noted. This novel case highlights the feasibility and safety of the use of intrapleural hyaluronidase in the management of hyaluronic acid-rich viscous malignant pleural effusion.
恶性胸腔积液在间皮瘤中很常见。我们报告一例粘性复发性恶性间皮瘤胸腔积液病例。其粘性是由于透明质酸的存在，导致引流时间延长。胸膜内使用透明质酸酶可显著降低液体粘度和引流持续时间。未观察到不良反应。这个新病例突出了胸膜内使用透明质酸酶治疗富含透明质酸的粘性恶性胸腔积液的可行性和安全性。
