Division of Thoracic Surgery, Sant'Andrea Hospital, Sapienza University of Rome, Italy.
Division of Thoracic Surgery, Sant'Andrea Hospital, Sapienza University of Rome, Italy.
Chest. 2021 Dec;160(6):e613-e617. doi: 10.1016/j.chest.2021.08.037.
This is the first report to our knowledge of a successful total tracheal replacement in a post-COVID-19 patient by cryopreserved aortic allograft. The graft was anastomosed to the cricoid and carina; a silicon stent was inserted to ensure patency. The patient was extubated on the operative table and was immediately able to breathe, speak, and swallow. No immunosuppression was administered. Three weeks after surgery, the patient was discharged from hospital in excellent health, and was able to resume his normal lifestyle, work, and activity as an amateur cyclist. Two months after surgery, the patient assumes aerosol with saline solution three times per day and no other therapy; routine bronchoscopy to clear secretions is no longer needed.
这是我们所知的首例通过冷冻保存的同种异体主动脉移植物成功对 COVID-19 后患者进行全气管置换的报告。移植物与环状软骨和隆突吻合；插入硅酮支架以确保通畅。患者在手术台上拔管，立即能够呼吸、说话和吞咽。未给予免疫抑制。术后 3 周，患者出院时身体状况极佳，能够恢复正常的生活方式、工作和业余自行车运动员的活动。术后 2 个月，患者每天用生理盐水吸入气雾剂 3 次，无需其他治疗；不再需要常规支气管镜清除分泌物。
