Human Performance and Sports Science Laboratory, Faculty of Sport Sciences, University of Murcia, Murcia, Spain.
Faculty of Physical Education and Sport, Charles University, Praha, Czech Republic.
BMJ Open. 2021 Dec 6;11(12):e052913. doi: 10.1136/bmjopen-2021-052913.
There is not a doubt that tailored exercise is an effective non-pharmacological approach for preventing, mitigating and even reversing ageing-related alterations. However, older adults are likely to experience prolonged periods of inactivity and training cessation periods as a consequence of falls or hospitalisation. Although recent evidence supports that exercise could have a protective effect and help in recovering, there is to date a lack of consensus about what kind of physical exercise prescription and training duration would produce better outcomes after training cessation periods. The current study will determine the effects that available exercise prescriptions produced in older adults in preserving physical conditioning following inactivity periods.
A systematic search of the literature will be conducted in three databases, namely PubMed, Scopus and Web of Science, from inception to 1 February 2021. Only randomised controlled trials written in English or Spanish will be eligible. No year of publication restriction will be applied. Eligible studies will contain information on population (older adults over 60 years old), intervention (inactivity period, exercise programme their duration), comparator (treatment as usual or waiting list) and outcomes (strength, functional capacity, metabolic health and skeletal muscle structure). Two independent reviewers will (1) search, screen and select studies, (2) extract data about their main characteristics and (3) evaluate their methodological and reporting quality. When disagreements emerge, the reviewers will discuss to reach a consensus. We plan to conduct meta-analysis to quantitatively synthesise the effects under study.
As systematic reviews use publicly available data, no formal ethical review and approval are needed. Findings will be published in a peer-reviewed journal(s) and presented at conferences.
CRD42021235092.
毫无疑问，定制运动是一种有效的非药物干预手段，可用于预防、减轻甚至逆转与衰老相关的变化。然而，老年人由于跌倒或住院等原因，很可能会经历长时间的不活动和训练中断期。尽管最近的证据表明，运动可能具有保护作用，并有助于康复，但迄今为止，对于在训练中断期后，什么样的体育锻炼处方和训练持续时间会产生更好的效果，还没有达成共识。本研究将确定现有的运动处方在保持老年人在不活动期后的身体适应能力方面的效果。
将在三个数据库中进行系统文献检索，即 PubMed、Scopus 和 Web of Science，检索时间从建库至 2021 年 2 月 1 日。只有用英文或西班牙文撰写的随机对照试验才符合条件。不限制发表年份。合格的研究将包含有关人群（60 岁以上的老年人）、干预（不活动期、运动方案及其持续时间）、对照（常规治疗或候补名单）和结果（力量、功能能力、代谢健康和骨骼肌结构）的信息。两名独立的审查员将（1）搜索、筛选和选择研究，（2）提取主要特征数据，以及（3）评估其方法学和报告质量。当出现分歧时，审查员将进行讨论以达成共识。我们计划进行荟萃分析，以定量综合研究中的效果。
由于系统评价使用公开可用的数据，因此不需要进行正式的伦理审查和批准。研究结果将发表在同行评议的期刊上，并在会议上展示。
PROSPERO 注册号：CRD42021235092。
