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慢性透析患者的生活质量评估:越南一家国家医院血液透析和腹膜透析的比较。

Quality of life assessment in patients on chronic dialysis: Comparison between haemodialysis and peritoneal dialysis at a national hospital in Vietnam.

机构信息

Department of Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam.

Department of Pharmacy, Thong Nhat Hospital, Ho Chi Minh City, Vietnam.

出版信息

Trop Med Int Health. 2022 Feb;27(2):199-206. doi: 10.1111/tmi.13709. Epub 2022 Jan 2.

Abstract

OBJECTIVES

End-stage renal disease (ESRD) is a chronic disease that can adversely affect the patient's quality of life (QoL) in terms of functional limitation and cognitive impairment. This study aimed to identify the factors associated with QoL in patients with ESRD undergoing dialysis at a national hospital in Vietnam.

METHODS

A descriptive cross-sectional study was conducted among outpatients aged ≥18 years who underwent haemodialysis (HD) or peritoneal dialysis (PD) for at least 3 months at Thong Nhat Hospital, Ho Chi Minh City, Vietnam from May 2020 to July 2021. QoL was measured using the validated Vietnamese version of the EuroQol-5 Dimensional-5 Level (EQ-5D-5L). The factors associated with the QoL of patients with ESRD undergoing dialysis were identified using multiple linear regression analysis.

RESULTS

In total, 131 (73.6%) and 47 (26.4%) patients underwent HD and PD, respectively. Overall, 178 (55.6%) patients were men (median age, 66 [56-79] years). The mean EQ-5D-5L score was significantly higher in patients undergoing PD than in those undergoing HD (0.848 ± 0.183 vs. 0.766 ± 0.231; p = 0.030). Older age (β = -0.006; p < 0.001) and peptic ulcer disease (β = -0.083; p = 0.029) were associated with lower QoL scores. PD treatment was associated with higher QoL scores (β = 0.065; p = 0.046).

CONCLUSIONS

It is necessary to improve the QoL of patients undergoing dialysis, especially of elderly patients and patients with peptic ulcer disease. PD may be a better method for maintenance dialysis, if applicable, in terms of QoL.

摘要

目的

终末期肾病(ESRD)是一种慢性病,会导致患者的生活质量(QoL)受到负面影响,出现功能受限和认知障碍等问题。本研究旨在确定越南一家国立医院接受透析治疗的 ESRD 患者的 QoL 相关因素。

方法

这是一项描述性的横断面研究,于 2020 年 5 月至 2021 年 7 月在越南胡志明市同奈医院选取年龄≥18 岁、接受血液透析(HD)或腹膜透析(PD)治疗至少 3 个月的门诊患者进行。采用经过验证的越南版 EuroQol-5 维度-5 级量表(EQ-5D-5L)来测量 QoL。采用多元线性回归分析确定与 ESRD 透析患者 QoL 相关的因素。

结果

共有 131 例(73.6%)和 47 例(26.4%)患者分别接受 HD 和 PD 治疗。总的来说,178 例(55.6%)患者为男性(中位年龄为 66 [56-79] 岁)。PD 组患者的 EQ-5D-5L 评分明显高于 HD 组(0.848±0.183 vs. 0.766±0.231;p=0.030)。年龄较大(β=-0.006;p<0.001)和消化性溃疡病(β=-0.083;p=0.029)与较低的 QoL 评分相关。PD 治疗与较高的 QoL 评分相关(β=0.065;p=0.046)。

结论

有必要改善透析患者的 QoL,尤其是老年患者和消化性溃疡病患者的 QoL。如果适用,PD 可能是一种更好的维持透析方法,可提高患者的 QoL。

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