Cameron A J, Higgins J A
Gastroenterology. 1986 Aug;91(2):338-42.
A prospective study was undertaken to identify mucosal lesions that might cause chronic blood loss anemia in patients with large diaphragmatic hernia. Patients with one-third or more of the stomach above the diaphragm on barium x-ray were examined by a gastroscopist who was given no clinical information. A total of 109 patients were included: 55 with anemia and 54 with a large hernia but no anemia. The incidence of esophagitis and peptic ulcer did not differ significantly in the anemic and nonanemic groups. Linear gastric erosions were found on the crests of mucosal folds at or near the level of the diaphragm in 23 anemic patients and 13 without anemia (p less than 0.05). Blood on the surface of a linear erosion was found in 14 anemic patients and 4 without anemia (p less than 0.05). We suggest that these erosions are due to trauma and can cause chronic blood loss anemia in hernia patients.
进行了一项前瞻性研究，以确定可能导致大型膈疝患者慢性失血性贫血的黏膜病变。对钡餐X线显示三分之一或更多胃位于膈肌上方的患者，由一名未获得临床信息的胃镜检查医生进行检查。总共纳入了109例患者：55例贫血患者和54例有大型疝但无贫血的患者。贫血组和非贫血组的食管炎和消化性溃疡发生率无显著差异。在23例贫血患者和13例无贫血患者的膈肌水平或其附近的黏膜皱襞嵴上发现了线性胃糜烂（p<0.05）。在14例贫血患者和4例无贫血患者的线性糜烂表面发现了血液（p<0.05）。我们认为这些糜烂是由创伤引起的，可导致疝患者慢性失血性贫血。
