Siegler Jason C, Carr Amelia J, Jardine William T, Convit Lilia, Cross Rebecca, Chapman Dale, Burke Louise M, Ross Megan
College of Health Solutions, Arizona State University, Phoenix, AZ,USA.
School of Science and Health, Western Sydney University, Campbelltown, NSW,Australia.
Int J Sport Nutr Exerc Metab. 2022 Mar 1;32(2):74-81. doi: 10.1123/ijsnem.2021-0179. Epub 2021 Dec 7.
Buffering agents have not been comprehensively profiled in terms of their capacity to influence water retention prior to exercise. The purpose of this investigation was to profile the fluid retention characteristics of sodium bicarbonate (BIC) and sodium citrate (CIT) to determine the efficacy of these buffering mediums as hyperhydrating agents. Nineteen volunteers (13 males and six females; age = 28.3 ± 4.9 years) completed three trials (randomized and cross-over design). For each trial, a baseline measurement of body mass, capillary blood, and urine was collected prior to ingestion of their respective condition (control condition [CON] = 25 ml/kg artificially sweetened water; BIC condition = CON + 7.5 g/L of sodium in the form of BIC; CIT condition = CON + 7.5 g/L of sodium in the form of CIT). The fluid loads were consumed in four equal aliquots (0, 20, 40 and 60 min; fluid intake was 1.972 ± 361 ml [CON]; 1.977 ± 360 ml [BIC]; 1.953 ± 352 ml [CIT]). Samples were recorded at 20 (body mass and urine) and 60 min (blood) intervals for 180 min. Blood buffering capacity (HCO3-) was elevated (p < .001) in both BIC (32.1 ± 2.2 mmol/L) and CIT (28.9 ± 3.8 mmol/L) at 180 min compared with CON (25.1 ± 1.8 mmol/L). Plasma volume expansion was greater (p < .001) in both BIC (8.1 ± 1.3%) and CIT (5.9 ± 1.8%) compared with CON (-1.1 ± 1.4%); whereas, total urine production was lower in BIC and CIT at 180 min (BIC vs. CON, mean difference of 370 ± 85 ml; p < .001; CIT vs. CON, mean difference of 239 ± 102 ml; p = .05). There were no increases observed in body mass (p = .9). Under resting conditions, these data suggest BIC and CIT induce a greater plasma hypervolemic response as compared with water alone.
就运动前影响水分潴留的能力而言，缓冲剂尚未得到全面分析。本研究的目的是分析碳酸氢钠（BIC）和柠檬酸钠（CIT）的液体潴留特性，以确定这些缓冲介质作为高水合作用剂的功效。19名志愿者（13名男性和6名女性；年龄=28.3±4.9岁）完成了三项试验（随机交叉设计）。对于每项试验，在摄入各自的溶液（对照溶液[CON]=25ml/kg人工甜味水；BIC溶液=CON+7.5g/L以BIC形式存在的钠；CIT溶液=CON+7.5g/L以CIT形式存在的钠）之前，收集体重、毛细血管血和尿液的基线测量值。液体负荷分四次等量摄入（0、20、40和60分钟；液体摄入量分别为1.972±361ml[CON]；1.977±360ml[BIC]；1.953±352ml[CIT]）。在180分钟内，每隔20分钟（体重和尿液）和60分钟（血液）记录一次样本。与CON（25.1±1.8mmol/L）相比，180分钟时BIC（32.1±2.2mmol/L）和CIT（28.9±3.8mmol/L）的血液缓冲能力（HCO3-）均升高（p<.001）。与CON（-1.1±1.4%）相比，BIC（8.1±1.3%）和CIT（5.9±1.8%）的血浆容量扩张更大（p<.001）；而在180分钟时，BIC和CIT的总尿量较低（BIC与CON相比，平均差异为370±85ml；p<.001；CIT与CON相比，平均差异为239±102ml；p=.05）。体重未见增加（p=.9）。在静息条件下，这些数据表明，与单独饮水相比，BIC和CIT可诱导更大的血浆高血容量反应。
