Komuro H, Sakai T, Hirota A, Kamino K
Jpn J Physiol. 1986;36(1):123-37. doi: 10.2170/jjphysiol.36.123.
Spontaneous action potentials were monitored from multiple sites in the bullfrog atrium using a voltage-sensitive merocyanine-rhodanine dye together with a 100-element photodiode matrix array, and we have assessed the spread of the excitation from the pacemaker. Isochrone curves of conduction were obtained by timing the initiation of the action potential-related optical signals: we constructed maps of the spread. Excitatory waves appeared to conduct radially from the pacemaking area over the atrium, and the conduction velocity in the left atrium exceeded that in the right atrium.
使用电压敏感染料部花青罗丹宁以及一个100元件光电二极管矩阵阵列,从牛蛙心房的多个部位监测自发动作电位,并且我们评估了兴奋从起搏器的传播情况。通过对动作电位相关光信号起始时间进行计时获得传导等时线曲线:我们构建了传播图谱。兴奋波似乎从起搏区域呈放射状传导至整个心房,并且左心房的传导速度超过右心房。