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通过动作电位的多位点光学记录评估两栖类心房的兴奋传导模式。

Conduction pattern of excitation in the amphibian atrium assessed by multiple-site optical recording of action potentials.

作者信息

Komuro H, Sakai T, Hirota A, Kamino K

出版信息

Jpn J Physiol. 1986;36(1):123-37. doi: 10.2170/jjphysiol.36.123.

DOI:10.2170/jjphysiol.36.123
PMID:3487666
Abstract

Spontaneous action potentials were monitored from multiple sites in the bullfrog atrium using a voltage-sensitive merocyanine-rhodanine dye together with a 100-element photodiode matrix array, and we have assessed the spread of the excitation from the pacemaker. Isochrone curves of conduction were obtained by timing the initiation of the action potential-related optical signals: we constructed maps of the spread. Excitatory waves appeared to conduct radially from the pacemaking area over the atrium, and the conduction velocity in the left atrium exceeded that in the right atrium.

摘要

使用电压敏感染料部花青罗丹宁以及一个100元件光电二极管矩阵阵列,从牛蛙心房的多个部位监测自发动作电位,并且我们评估了兴奋从起搏器的传播情况。通过对动作电位相关光信号起始时间进行计时获得传导等时线曲线:我们构建了传播图谱。兴奋波似乎从起搏区域呈放射状传导至整个心房,并且左心房的传导速度超过右心房。

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1
Conduction pattern of excitation in the amphibian atrium assessed by multiple-site optical recording of action potentials.通过动作电位的多位点光学记录评估两栖类心房的兴奋传导模式。
Jpn J Physiol. 1986;36(1):123-37. doi: 10.2170/jjphysiol.36.123.
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Flexibility of regional pacemaking priority in early embryonic heart monitored by simultaneous optical recording of action potentials from multiple sites.通过对多个位点动作电位的同步光学记录监测早期胚胎心脏中区域起搏优先性的灵活性。
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Optical mapping of the spread of excitation in the isolated rat atrium during tachycardia-like excitation.在类似心动过速的兴奋过程中对离体大鼠心房兴奋传播的光学映射。
Pflugers Arch. 2003 Dec;447(3):280-8. doi: 10.1007/s00424-003-1185-x. Epub 2003 Oct 25.
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Evaluation of optimal voltage-sensitive dyes for optical monitoring of embryonic neural activity.
用于胚胎神经活动光学监测的最佳电压敏感染料的评估。
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Design of a multi-point laser scanned optical monitor of cardiac action potential propagation: application to microreentry in guinea pig atrium.
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Mapping of early development of electrical activity in the embryonic chick heart using multiple-site optical recording.利用多部位光学记录绘制胚胎期鸡心脏电活动的早期发育图谱。
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