Haneef Zulfi, Karimov Alexandr, Krishnan Vaishnav, Sheth Sameer A
Department of Neurology, Baylor College of Medicine, Houston, Texas, United States.
Department of Neurosurgery, Baylor College of Medicine, Houston, Texas, United States.
Surg Neurol Int. 2021 Nov 23;12:577. doi: 10.25259/SNI_692_2021. eCollection 2021.
The responsive neurostimulation system (RNS) is used in patients with drug-resistant epilepsy who are not candidates for surgical resection of a seizure focus. As a relatively new therapy option, the adverse effects of long-term implantation are still being clarified. We present a series of two patients who presented with similar symptoms which were attributable to migration of the intracranially implanted subdural leads.
Two patients who had subdural RNS lead implantation presented with symptoms of paroxysmal unilateral facial pain which were thought to be related to the stimulation of the trigeminal nerve secondary to RNS lead migration. Adjustment of the stimulation parameters improved the symptoms in both patients.
Chronically implanted subdural RNS leads can migrate over time stimulating nerves in the intracranial space. Strategies to avoid and overcome the complication are discussed.
响应性神经刺激系统（RNS）用于药物难治性癫痫且不适合进行癫痫病灶手术切除的患者。作为一种相对较新的治疗选择，长期植入的不良反应仍在阐明中。我们报告了一系列两名患者，他们出现了类似的症状，这些症状归因于颅内植入的硬膜下电极的移位。
两名接受硬膜下RNS电极植入的患者出现阵发性单侧面部疼痛症状，认为与RNS电极移位继发的三叉神经刺激有关。刺激参数的调整改善了两名患者的症状。
长期植入的硬膜下RNS电极可能会随着时间推移而移位，刺激颅内空间的神经。讨论了避免和克服该并发症的策略。
