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硫酸钙抗生素珠粒用于腹壁重建术后白色念珠菌引起的生物补片感染:一例报告

Biologic mesh infection with Candida albicans after abdominal wall reconstruction with calcium sulphate antibiotic beads: A case report.

作者信息

Brennan Kelly, Patel Pooja, Drohan Ashley, Minor Samuel

机构信息

Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.

Department of General Surgery, Dalhousie University, Halifax, Nova Scotia, Canada.

出版信息

IDCases. 2021 Nov 24;26:e01351. doi: 10.1016/j.idcr.2021.e01351. eCollection 2021.

Abstract

Mesh infection after abdominal wall reconstruction is a rare and usually devastating complication. Herein, we describe a unique case of a delayed and non-lethal Candida albicans mesh infection after abdominal wall reconstruction with placement of a biologic graft impregnated with antibiotics. Mesh explantation was not required, and the wound healed by secondary intention. This work suggests that locally delivered antibiotics may change the culprit microbes of skin infections to more unusual species such as Candida spp. Future research is required to study the effect of including antifungal agents in the locally delivered antimicrobials for abdominal wall reconstructions with biological meshes.

摘要

腹壁重建术后的补片感染是一种罕见且通常具有毁灭性的并发症。在此,我们描述了一例独特的病例,在腹壁重建并植入含抗生素的生物移植物后发生了延迟性且非致命的白色念珠菌补片感染。无需取出补片,伤口通过二期愈合。这项研究表明,局部应用抗生素可能会使皮肤感染的致病微生物转变为更不常见的菌种,如念珠菌属。未来需要开展研究,以探讨在用于腹壁重建的生物补片中,局部应用抗菌药物时加入抗真菌药物的效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c369/8633862/f8fcd5b0f3ed/gr1.jpg

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