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肝结核误诊为胆管癌:一例报告

Misidentification of hepatic tuberculosis as cholangiocarcinoma: A case report.

作者信息

Li Wei, Tang Yan-Fen, Yang Xue-Feng, Huang Xiang-Yu

机构信息

The Affiliated Nanhua Hospital, Department of Radiology, Hengyang Medical School, University of South China, Hengyang 421002, Hunan Province, China.

The Affiliated Nanhua Hospital, Department of Gastroenterology, Hengyang Medical School, University of South China, Hengyang 421002, Hunan Province, China.

出版信息

World J Clin Cases. 2021 Nov 6;9(31):9662-9669. doi: 10.12998/wjcc.v9.i31.9662.

DOI:10.12998/wjcc.v9.i31.9662
PMID:34877304
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8610856/
Abstract

BACKGROUND

Hepatic tuberculosis (TB) is uncommon clinically. Because of a lack of specific signs, characteristic symptoms and clinical manifestations and because pathological samples are difficult to obtain, hepatic TB is easily missed or misdiagnosed.

CASE SUMMARY

A 62-year-old Chinese man presented with jaundice for 1 wk and no abnormal laboratory tests other than elevated bilirubin, aminotransferases and C-reactive protein. Computed tomography (CT) of the abdomen showed a mass in the left lobe of the liver and hepatic hilum with striped calcified foci. Mild enhancement was visible at the edges, along with extensive intrahepatic biliary ductal dilatation in the right lobe of the liver. In the arterial phase of both CT and magnetic resonance imaging, the main trunk and right branch of the portal artery were partially visualized. Magnetic resonance cholangiopancreatography (MRCP) indicated that the left lobe of the liver and most of the bile ducts in the hilum were not visible. Pathological examination revealed coagulative necrosis, and granulomatous nodules were seen around areas of necrosis; therefore, TB was considered.

CONCLUSION

Hepatic tuberculosis is easily misdiagnosed or missed on imaging. Percutaneous puncture biopsy is the most useful tool for definitive diagnosis.

摘要

背景

肝结核在临床上并不常见。由于缺乏特异性体征、特征性症状和临床表现,且病理样本难以获取,肝结核很容易被漏诊或误诊。

病例摘要

一名62岁中国男性因黄疸1周就诊,除胆红素、转氨酶和C反应蛋白升高外,实验室检查无异常。腹部计算机断层扫描(CT)显示肝左叶和肝门区有一肿块,伴有条纹状钙化灶。边缘可见轻度强化,同时肝右叶肝内胆管广泛扩张。在CT和磁共振成像的动脉期,门静脉主干和右支部分显影。磁共振胰胆管造影(MRCP)显示肝左叶及肝门区大部分胆管未见显影。病理检查显示凝固性坏死,坏死区域周围可见肉芽肿结节,因此考虑为结核。

结论

肝结核在影像学上容易被误诊或漏诊。经皮穿刺活检是明确诊断的最有用工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bab3/8610856/a622fda31c66/WJCC-9-9662-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bab3/8610856/1d2bfc996bc5/WJCC-9-9662-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bab3/8610856/5bced762be82/WJCC-9-9662-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bab3/8610856/a622fda31c66/WJCC-9-9662-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bab3/8610856/1d2bfc996bc5/WJCC-9-9662-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bab3/8610856/5bced762be82/WJCC-9-9662-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bab3/8610856/a622fda31c66/WJCC-9-9662-g003.jpg

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Infez Med. 2020 Sep 1;28(3):420-424.
2
Hepatic tuberculosis masquerading as cholangiocarcinoma: an unusual differential for a liver mass.伪装成胆管癌的肝结核:肝脏肿块的一种不寻常鉴别诊断。
J Surg Case Rep. 2020 Aug 27;2020(8):rjaa247. doi: 10.1093/jscr/rjaa247. eCollection 2020 Aug.
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Looking beyond appearances: when liver biopsy is the key for hepatic tuberculosis diagnosis.抛开表象:肝活检在肝结核诊断中的关键作用。
BMJ Case Rep. 2020 May 5;13(5):e234491. doi: 10.1136/bcr-2020-234491.
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Tubercular granuloma mimicking pyogenic liver abscess.酷似化脓性肝脓肿的结核性肉芽肿。
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Tuberculosis masquerading as metastasis in liver: a rare and an unusual presentation.伪装成肝转移的肺结核:一种罕见且不寻常的表现。
BMJ Case Rep. 2020 Feb 19;13(2):e233303. doi: 10.1136/bcr-2019-233303.
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Diagnosis and treatment of congenital tuberculosis: a systematic review of 92 cases.先天性结核病的诊断与治疗:92 例病例的系统回顾
Orphanet J Rare Dis. 2019 Jun 10;14(1):131. doi: 10.1186/s13023-019-1101-x.
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Primary hepatic tuberculosis masquerading as intrahepatic cholangiocarcinoma.伪装成肝内胆管癌的原发性肝结核。
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Tuberculosis (TB) of the Porta Hepatis Presenting with Obstructive Jaundice Mimicking a Malignant Biliary Tumor: A Case Report and Review of the Literature.以阻塞性黄疸表现、酷似恶性胆管肿瘤的肝门部结核:一例报告并文献复习
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