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胃肠道症状作为新生儿慢性肉芽肿病的首发体征:一例病例报告。

Gastrointestinal symptoms as the first sign of chronic granulomatous disease in a neonate: A case report.

作者信息

Meng Er-Yan, Wang Zi-Ming, Lei Bing, Shang Li-Hong

机构信息

Division of Neonatology, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan Province, China.

Chongqing Medical College, Chongqing 400016, China.

出版信息

World J Clin Cases. 2021 Nov 16;9(32):9997-10005. doi: 10.12998/wjcc.v9.i32.9997.

DOI:10.12998/wjcc.v9.i32.9997
PMID:34877342
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8610891/
Abstract

BACKGROUND

Chronic granulomatous disease (CGD) characterized by recurrent and severe bacterial and fungal infections is most common in childhood.

CASE SUMMARY

We reported a 24-d-old male infant who developed gastrointestinal symptoms as the first sign of CGD.

CONCLUSION

Gastrointestinal symptoms representing the first sign of CGD are very rare, and prompt diagnosis and treatment with broad-spectrum antibiotics were of crucial importance.

摘要

背景

慢性肉芽肿病(CGD)以反复严重的细菌和真菌感染为特征,在儿童期最为常见。

病例摘要

我们报告了一名24日龄男婴,其出现胃肠道症状作为CGD的首发体征。

结论

以胃肠道症状作为CGD首发体征非常罕见,及时诊断并用广谱抗生素治疗至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8de/8610891/2860638865e9/WJCC-9-9997-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8de/8610891/64f84fe0a0dd/WJCC-9-9997-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8de/8610891/3a28318c0168/WJCC-9-9997-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8de/8610891/2621dbe878d1/WJCC-9-9997-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8de/8610891/a7dfc0e1cd97/WJCC-9-9997-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8de/8610891/09b1f3e77cf0/WJCC-9-9997-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8de/8610891/2860638865e9/WJCC-9-9997-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8de/8610891/64f84fe0a0dd/WJCC-9-9997-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8de/8610891/3a28318c0168/WJCC-9-9997-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8de/8610891/2621dbe878d1/WJCC-9-9997-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8de/8610891/a7dfc0e1cd97/WJCC-9-9997-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8de/8610891/09b1f3e77cf0/WJCC-9-9997-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8de/8610891/2860638865e9/WJCC-9-9997-g006.jpg

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本文引用的文献

1
[Chronic granulomatous disease as a rare differential diagnosis of inflammatory bowel disease].
Z Gastroenterol. 2018 Dec;56(12):1507-1512. doi: 10.1055/a-0732-5865. Epub 2018 Nov 22.
2
Chronic granulomatous disease: Clinical, functional, molecular, and genetic studies. The Israeli experience with 84 patients.慢性肉芽肿病:临床、功能、分子和遗传研究。以色列 84 例患者的经验。
Am J Hematol. 2017 Jan;92(1):28-36. doi: 10.1002/ajh.24573. Epub 2016 Nov 18.
3
Gastrointestinal Features of Chronic Granulomatous Disease Found During Endoscopy.内镜检查中发现的慢性肉芽肿病的胃肠道特征
Clin Gastroenterol Hepatol. 2016 Mar;14(3):395-402.e5. doi: 10.1016/j.cgh.2015.10.030. Epub 2015 Nov 9.
4
Rare diagnosis in a neonate who presents with fever.一名发热新生儿的罕见诊断。
Clin Pediatr (Phila). 2015 Jan;54(1):91-3. doi: 10.1177/0009922814541809. Epub 2014 Jul 14.
5
Clinical and molecular features of 38 children with chronic granulomatous disease in mainland china.中国大陆38例慢性肉芽肿病患儿的临床及分子特征
J Clin Immunol. 2014 Aug;34(6):633-41. doi: 10.1007/s10875-014-0061-0. Epub 2014 Jun 19.
6
Clinical, functional, and genetic characterization of chronic granulomatous disease in 89 Turkish patients.89 例土耳其慢性肉芽肿病患者的临床、功能和基因特征。
J Allergy Clin Immunol. 2013 Nov;132(5):1156-1163.e5. doi: 10.1016/j.jaci.2013.05.039. Epub 2013 Jul 31.
7
Clinical outcome in children with chronic granulomatous disease managed conservatively or with hematopoietic stem cell transplantation.慢性肉芽肿病患儿采用保守治疗或造血干细胞移植治疗的临床结局。
J Allergy Clin Immunol. 2013 Nov;132(5):1150-5. doi: 10.1016/j.jaci.2013.05.031. Epub 2013 Jul 16.
8
Invasive mold infections in chronic granulomatous disease: a 25-year retrospective survey.慢性肉芽肿病中的侵袭性霉菌感染:一项 25 年回顾性调查。
Clin Infect Dis. 2011 Dec;53(12):e159-69. doi: 10.1093/cid/cir731.
9
Residual NADPH oxidase and survival in chronic granulomatous disease.慢性肉芽肿病中残余烟酰胺腺嘌呤二核苷酸磷酸氧化酶与生存。
N Engl J Med. 2010 Dec 30;363(27):2600-10. doi: 10.1056/NEJMoa1007097.
10
Therapeutic strategy in p47-phox deficient chronic granulomatous disease presenting as inflammatory bowel disease.表现为炎症性肠病的p47-吞噬氧化酶缺陷慢性肉芽肿病的治疗策略。
J Allergy Clin Immunol. 2010 Apr;125(4):943-946.e1. doi: 10.1016/j.jaci.2010.01.035.