Jiang Zhen-Zhen, Zheng Yuan-Yuan, Hou Chuan-Ling, Liu Xia-Tian
Department of Ultrasound, Shaoxing People's Hospital (Shaoxing Hospital, Zhejiang University School of Medicine), Shaoxing 312000, Zhejiang Province, China.
Department of Pathology, Shaoxing People's Hospital (Shaoxing Hospital, Zhejiang University School of Medicine), Shaoxing 312000, Zhejiang Province, China.
World J Clin Cases. 2021 Nov 16;9(32):10024-10032. doi: 10.12998/wjcc.v9.i32.10024.
Mucosal-associated lymphoid tissue extranodal marginal zone (MALT) lymphoma is a low-grade tumor that rarely occurs in the urinary bladder. There is currently no consensus on the common imaging findings or most appropriate treatment in MALT lymphoma in the urinary bladder due to the limited number of reports.
A 48-year-old woman was admitted to the hospital with a 1-year history of macroscopic hematuria. Imaging showed a large homogeneous mass with an unclear boundary and an irregular morphology in the bladder. The mass had an abundant blood supply. For further diagnosis, transurethral cystoscopic biopsy and bone marrow biopsy was performed, and the patient was finally diagnosed with primary MALT lymphoma of the bladder. R-CHOP chemotherapy was carried out. After three cycles of chemotherapy, the mass disappeared and the bladder wall thickness was only 4 mm, which indicated excellent therapeutic response to the chemotherapy. To date, the patient remains asymptomatic and she visits our hospital regularly for the completion of the remaining chemotherapy cycles.
Primary MALT lymphoma of the bladder is rare, and there are certain characteristics in the ultrasonographic findings. Imaging findings play an important role in evaluating the therapeutic efficacy and are critical during long-term follow-up after therapy.
黏膜相关淋巴组织结外边缘区（MALT）淋巴瘤是一种低度恶性肿瘤，很少发生于膀胱。由于报道数量有限，目前对于膀胱MALT淋巴瘤的常见影像学表现或最合适的治疗方法尚无共识。
一名48岁女性因肉眼血尿1年入院。影像学检查显示膀胱内有一个边界不清、形态不规则的巨大均匀肿块。该肿块血供丰富。为进一步诊断，进行了经尿道膀胱镜活检和骨髓活检，最终患者被诊断为原发性膀胱MALT淋巴瘤。采用R-CHOP化疗方案。化疗三个周期后，肿块消失，膀胱壁厚度仅为4mm，表明化疗疗效极佳。迄今为止，患者无症状，定期来我院完成剩余化疗周期。
原发性膀胱MALT淋巴瘤罕见，超声检查有一定特征。影像学检查在评估治疗效果中起重要作用，在治疗后的长期随访中至关重要。
