自闭症谱系障碍中的遗传和表观遗传改变。
Genetic and Epigenetic Alterations in Autism Spectrum Disorder.
作者信息
Oztenekecioglu Bugsem, Mavis Merdiye, Osum Meryem, Kalkan Rasime
机构信息
Department of Molecular Biology and Genetics, Faculty of Arts and Sciences, Near East University, Nicosia, Cyprus.
Department of Medical Genetics, Faculty of Medicine, Near East University, Nicosia, Cyprus.
出版信息
Glob Med Genet. 2021 Sep 15;8(4):144-148. doi: 10.1055/s-0041-1735540. eCollection 2021 Dec.
Abstract
It is extremely important to understand the causes of autism spectrum disorder (ASD) which is a neurodevelopmental disease. Treatment and lifelong support of autism are also important to improve the patient's life quality. In this article, several findings were explained to understand the possible causes of ASD. We draw, outline, and describe ASD and its relation with the epigenetic mechanisms. Here, we discuss, several different factors leading to ASD such as environmental, epigenetic, and genetic factors.
摘要
了解自闭症谱系障碍（ASD）这一神经发育疾病的病因极其重要。自闭症的治疗和终身支持对于提高患者生活质量也很重要。在本文中，阐述了几项研究结果以了解ASD的可能病因。我们绘制、概述并描述了ASD及其与表观遗传机制的关系。在此，我们讨论了导致ASD的几个不同因素，如环境、表观遗传和遗传因素。
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