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Epigenetics and Autism Spectrum Disorder: Is There a Correlation?

作者信息

Eshraghi Adrien A, Liu George, Kay Sae-In Samantha, Eshraghi Rebecca S, Mittal Jeenu, Moshiree Baharak, Mittal Rahul

机构信息

Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, FL, United States.

Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, FL, United States.

出版信息

Front Cell Neurosci. 2018 Mar 27;12:78. doi: 10.3389/fncel.2018.00078. eCollection 2018.

DOI:10.3389/fncel.2018.00078
PMID:29636664
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5881102/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c646/5881102/442c4c6ddfeb/fncel-12-00078-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c646/5881102/442c4c6ddfeb/fncel-12-00078-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c646/5881102/442c4c6ddfeb/fncel-12-00078-g0001.jpg

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Microglia from offspring of dams with allergic asthma exhibit epigenomic alterations in genes dysregulated in autism.母体过敏哮喘后代的小胶质细胞中，自闭症相关基因表现出表观遗传改变。
Glia. 2018 Mar;66(3):505-521. doi: 10.1002/glia.23261. Epub 2017 Nov 14.
3
Epigenetics at the crossroads between genes, environment and resilience in anxiety disorders.
Decoding Variants: Bridging Genetics and Phenotypes in Autism Spectrum Disorder.
解码变异：弥合自闭症谱系障碍中的遗传学与表型之间的差距
J Clin Med. 2025 May 28;14(11):3790. doi: 10.3390/jcm14113790.
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Molecular basis of autism spectrum disorders.自闭症谱系障碍的分子基础
Mol Biol Rep. 2025 May 28;52(1):508. doi: 10.1007/s11033-025-10604-1.
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Epigenetics Modulators as Therapeutics for Neurological Disorders.表观遗传学调节剂作为神经系统疾病的治疗方法
Curr Pharm Des. 2025;31(19):1499-1520. doi: 10.2174/0113816128330087241030093112.
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Unveiling the role of phytochemicals in autism spectrum disorder by employing network pharmacology and molecular dynamics simulation.揭示植物化学物质在自闭症谱系障碍中的作用：运用网络药理学和分子动力学模拟。
Metab Brain Dis. 2024 Nov 21;40(1):34. doi: 10.1007/s11011-024-01467-9.
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Dopamine Dysregulation in Reward and Autism Spectrum Disorder.奖励与自闭症谱系障碍中的多巴胺失调
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