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当讨论癌症药物对健康相关生活质量的影响时，患者和临床医生关心什么？前列腺癌中基于共识的混合方法研究。

What matters to patients and clinicians when discussing the impact of cancer medicines on health-related quality of life? Consensus-based mixed methods approach in prostate cancer.

机构信息

Strathclyde Institute of Pharmacy & Biomedical Sciences (SIPBS), University of Strathclyde, Glasgow, UK.

NHS Greater Glasgow & Clyde, Glasgow, UK.

出版信息

Support Care Cancer. 2022 Apr;30(4):3141-3150. doi: 10.1007/s00520-021-06724-6. Epub 2021 Dec 8.

DOI:10.1007/s00520-021-06724-6
PMID:34878587
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8857102/
Abstract

OBJECTIVE

To identify what matters to clinicians and patients when discussing cancer medicines' impact on health-related quality of life (HRQoL).

METHODS

A framework of HRQoL domain/domain elements was developed, informed by analysis of published patient reported outcome measures (PROMs), applicable to prostate cancer. Using mixed methods (eDelphi, Nominal Group Technique and questionnaire), prostate cancer clinicians and patients attending prostate cancer clinics and support groups were asked which domains/domain elements would be important to them when discussing the impact prostate cancer medicines have on their HRQoL.

RESULTS

Twenty-one clinicians and 71 patients participated from the West of Scotland. Clinicians and patients identified 53/62 domain elements across seven domains as important, of which 32 (60%) were common to both groups. Clinicians placed more importance than patients on Mood & Emotion; in contrast, patients placed importance on a broader range of Symptoms & Side Effects, being informed about their care, and having effective healthcare professional collaboration.

CONCLUSION

This study provides insight into the similarities and differences between what clinicians and patients think is important when discussing the impact of cancer medicines on HRQoL. Future research should involve exploring the potential for consistency of medicines PROMs across different cancer types to support patient-clinician communication and drive improvements in care.

摘要

目的

确定在讨论癌症药物对健康相关生活质量（HRQoL）的影响时，临床医生和患者关注的重点。

方法

根据已发表的患者报告结局测量（PROM）的分析，制定了一个适用于前列腺癌的 HRQoL 领域/领域要素框架。使用混合方法（eDelphi、名义群体技术和问卷调查），向在苏格兰西部就诊的前列腺癌临床医生和患者询问在讨论前列腺癌药物对其 HRQoL 的影响时，哪些领域/领域要素对他们很重要。

结果

21 名临床医生和 71 名患者参与了研究。临床医生和患者确定了 7 个领域中的 53/62 个领域要素很重要，其中 32 个（60%）是两组共同的。临床医生比患者更重视情绪和情感；相比之下，患者更关注更广泛的症状和副作用、了解他们的治疗情况以及有效进行医疗专业合作。

结论

本研究深入了解了在讨论癌症药物对 HRQoL 的影响时，临床医生和患者的关注点的异同。未来的研究应该探讨不同癌症类型的药物 PROM 之间是否具有一致性的潜力，以支持患者-临床医生的沟通，并推动护理的改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c4d/8857102/54f23ba6f737/520_2021_6724_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c4d/8857102/b84e2310ddb5/520_2021_6724_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c4d/8857102/201aa279f004/520_2021_6724_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c4d/8857102/54f23ba6f737/520_2021_6724_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c4d/8857102/b84e2310ddb5/520_2021_6724_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c4d/8857102/201aa279f004/520_2021_6724_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c4d/8857102/54f23ba6f737/520_2021_6724_Fig3_HTML.jpg

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本文引用的文献

1
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2
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Urol Pract. 2019 Jul 1;6(4):234-242. doi: 10.1097/UPJ.0000000000000020.
3
Maximising the impact of patient reported outcome assessment for patients and society.
让患者和临床医生参与癌症药物临床护理中电子患者报告结局指标的线框设计：混合方法研究
JMIR Form Res. 2023 Dec 21;7:e48296. doi: 10.2196/48296.
4
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Int J Gen Med. 2022 Sep 7;15:7123-7130. doi: 10.2147/IJGM.S253183. eCollection 2022.
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BMJ. 2019 Jan 24;364:k5267. doi: 10.1136/bmj.k5267.
4
Management of advanced prostate cancer: A systematic review of existing guidelines and recommendations.晚期前列腺癌的治疗管理：现有指南和建议的系统评价。
Cancer Treat Rev. 2019 Feb;73:54-61. doi: 10.1016/j.ctrv.2018.11.005. Epub 2018 Dec 1.
5
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7
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9
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10
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