Kim Ji-Soo, Kim Hyo-Jung
Department of Neurology, Seoul National University College of Medicine, Seoul.
Dizziness Center, Clinical Neuroscience Center, and Department of Neurology, Seoul National University Bundang Hospital, Seongnam.
Curr Opin Neurol. 2022 Feb 1;35(1):98-106. doi: 10.1097/WCO.0000000000001014.
The current review covers recent advances in bilateral vestibulopathy (BVP) in terms of its etiology, diagnosis, and treatments.
The etiology of BVP depends on its clinical course and associated findings, and genetic abnormalities are increasingly recognized in isolated as well as complicated form of BVP. Recent developments in evaluation of the vestibular function have greatly enhanced the detection of BVP, and introduction of the consensus diagnostic criteria by Barany Society has facilitated research on BVP. Vestibular prosthesis may improve vestibular function, posture, gait and quality of life in patients with BVP and would expand the therapeutic options for BVP in near future.
Genetics is expanding its role in identifying the causes of BVP of hitherto unknown etiology. The detection and investigation of BVP have been greatly enhanced by introduction of consensus diagnostic criteria and recent developments in methodology evaluating the vestibular function. Vestibular prothesis appears promising in managing BVP.
本综述涵盖双侧前庭病（BVP）在病因、诊断和治疗方面的最新进展。
BVP的病因取决于其临床病程及相关表现，遗传异常在孤立型和复杂型BVP中越来越受到认可。前庭功能评估的最新进展极大地提高了BVP的检出率，巴拉尼协会共识诊断标准的引入推动了BVP的研究。前庭假体可能改善BVP患者的前庭功能、姿势、步态和生活质量，并将在不久的将来扩大BVP的治疗选择。
遗传学在确定迄今病因不明的BVP病因方面的作用正在扩大。共识诊断标准的引入以及评估前庭功能方法的最新进展极大地加强了BVP的检测和研究。前庭假体在治疗BVP方面似乎很有前景。
