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Natural history of NAFLD: knowns and unknowns.

作者信息

Tsochatzis Emmanuel A

机构信息

UCL Institute for Liver and Digestive Health, Royal Free Hospital and UCL, London, UK.

出版信息

Nat Rev Gastroenterol Hepatol. 2022 Mar;19(3):151-152. doi: 10.1038/s41575-021-00565-8.

DOI:10.1038/s41575-021-00565-8
PMID:34880412
Abstract
摘要

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Alcoholic liver disease presents at advanced stage and progresses faster compared to non-alcoholic fatty liver diseas.酒精性肝病在晚期出现，与非酒精性脂肪性肝病相比进展更快。
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Active role of the immune system in metabolic dysfunction-associated steatotic liver disease.

本文引用的文献

1
Advancing the global public health agenda for NAFLD: a consensus statement.推进非酒精性脂肪性肝病的全球公共卫生议程：共识声明。
Nat Rev Gastroenterol Hepatol. 2022 Jan;19(1):60-78. doi: 10.1038/s41575-021-00523-4. Epub 2021 Oct 27.
免疫系统在代谢功能障碍相关脂肪性肝病中的积极作用。
Gastroenterol Rep (Oxf). 2024 Oct 15;12:goae089. doi: 10.1093/gastro/goae089. eCollection 2024.
4
miR-21: A therapeutic target for delaying severe liver disease and hepatocellular carcinoma in high-fat-diet-fed mice.微小RNA-21：高脂饮食喂养小鼠中延缓严重肝病和肝细胞癌的治疗靶点
bioRxiv. 2024 Oct 5:2024.09.19.613915. doi: 10.1101/2024.09.19.613915.
5
Strong associations between fasting lipids and glucose concentrations and ALT levels strengthened with increasing ALT quantiles.空腹血脂和血糖浓度与 ALT 水平之间的强烈关联随着 ALT 分位数的增加而增强。
Lipids Health Dis. 2024 Sep 12;23(1):295. doi: 10.1186/s12944-024-02281-z.
6
Incremental Value of Blood-Based Markers of Liver Fibrosis in Cardiovascular Risk Stratification.肝脏纤维化血液标志物在心血管风险分层中的增量价值。
J Clin Endocrinol Metab. 2025 Mar 17;110(4):1115-1127. doi: 10.1210/clinem/dgae619.
7
Immune system dysregulation in the pathogenesis of non-alcoholic steatohepatitis: unveiling the critical role of T and B lymphocytes.非酒精性脂肪性肝炎发病机制中的免疫系统失调：揭示 T 和 B 淋巴细胞的关键作用。
Front Immunol. 2024 Aug 1;15:1445634. doi: 10.3389/fimmu.2024.1445634. eCollection 2024.
8
Impact of -odontogenic infection on the pathogenesis of non-alcoholic fatty liver disease.- 牙源性感染对非酒精性脂肪性肝病发病机制的影响。
Ann Med. 2023;55(2):2255825. doi: 10.1080/07853890.2023.2255825.
9
MicroRNA regulation of AMPK in nonalcoholic fatty liver disease.微小 RNA 对非酒精性脂肪性肝病 AMPK 的调控作用。
Exp Mol Med. 2023 Sep;55(9):1974-1981. doi: 10.1038/s12276-023-01072-3. Epub 2023 Sep 1.
10
PM air pollution exposure and nonalcoholic fatty liver disease in the Nationwide Inpatient Sample.大气细颗粒物污染暴露与全国住院患者样本中的非酒精性脂肪肝
Environ Res. 2022 Oct;213:113611. doi: 10.1016/j.envres.2022.113611. Epub 2022 Jun 7.