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[同基因胸腺细胞对小鼠小肠上皮细胞增殖的影响]

[Effect of syngeneic thymocytes on the proliferation of the small intestine epithelium in mice].

作者信息

Shmakov A N, Aparovich G G, Trufakin V A

出版信息

Biull Eksp Biol Med. 1986 Jul;102(7):84-6.

PMID:3488084
Abstract

The effect of syngeneic thymocytes on the proliferative compartment of the small intestinal epithelium was studied in CBA mice. In mice that intravenously received thymus cells, the proliferative enterocyte activity was depressed, the proliferative zone reduced and the maturation zone enlarged. The data obtained indicate that medullary thymocytes are responsible for this effect. The regulatory role of the immune system with regard to cell proliferation is discussed.

摘要

在CBA小鼠中研究了同基因胸腺细胞对小肠上皮增殖区室的影响。在静脉注射胸腺细胞的小鼠中,增殖性肠上皮细胞活性降低,增殖区缩小,成熟区扩大。所获得的数据表明,髓质胸腺细胞是造成这种影响的原因。文中讨论了免疫系统对细胞增殖的调节作用。

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