Aparovich G G, Trufakin V A
Biull Eksp Biol Med. 1984 Oct;98(10):489-91.
The possibilities of inducing immunocompetent tissue-dependent changes were studied with the help of the intestinal epithelium model. It was found that thymectomy of adult mice or transplantation of syngeneic thymocytes to recipients with normal intestine function did not lead to changes in the intestinal epithelium whereas the injection of antilymphocyte serum or thymocytes to fasting mice resulted in the diminution of the size of the stem department, inhibition of the mitotic activity, and appearance of dystrophic changes in the intestinal epithelium. It is suggested that population changes in the lymphoid tissue may lead to alterations in the intestinal epithelial cells with different degree of maturity.
