在乌拉坦麻醉大鼠额叶皮质中与辨别性条件反射相关的慢电位和单单位反应。

Discriminative conditioning-related slow potential and single-unit responses in the frontal cortex of urethane-anesthetized rats.

作者信息

Rucker H K, Corbus M J, Pirch J H

出版信息

Brain Res. 1986 Jun 25;376(2):368-72. doi: 10.1016/0006-8993(86)90201-5.

Abstract

A model is described for obtaining long-term and stable discriminative conditioning-related slow-potential and single-unit responses from the frontal cortex of urethane-anesthetized rats. Responses were recorded and analyzed to reinforced (rewarding medial forebrain bundle stimulation) and non-reinforced tone cues. In the present study, cortical event-related slow potentials provided an adequate index of the level of discriminative conditioning. Single-unit response patterns are described for 57 neurons which demonstrated a discriminative response to either the reinforced or non-reinforced tone cue.

摘要

本文描述了一种从氨基甲酸乙酯麻醉大鼠的额叶皮质获取与辨别性条件反射相关的长期稳定慢电位和单神经元反应的模型。记录并分析了对强化（奖励性内侧前脑束刺激）和非强化音调线索的反应。在本研究中，皮质事件相关慢电位为辨别性条件反射水平提供了充分的指标。描述了57个神经元的单神经元反应模式，这些神经元对强化或非强化音调线索表现出辨别性反应。