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儿童和青少年乳制品总摄入量与超重及肥胖的关系:一项系统评价与荟萃分析。

Total dairy consumption in relation to overweight and obesity in children and adolescents: A systematic review and meta-analysis.

作者信息

Babio Nancy, Becerra-Tomás Nerea, Nishi Stephanie K, López-González Leyre, Paz-Graniel Indira, García-Gavilán Jesús, Schröder Helmut, Martín-Calvo Nerea, Salas-Salvadó Jordi

机构信息

Universitat Rovira i Virgili, Departament de Bioquímica i Biotecnologia, Unitat de Nutrició Humana. Hospital Universitari San Joan de Reus, Reus, Spain.

Institut d'Investigació Pere Virgili (IISPV), Reus, Spain.

出版信息

Obes Rev. 2022 Jan;23 Suppl 1:e13400. doi: 10.1111/obr.13400. Epub 2021 Dec 8.

Abstract

A systematic review and meta-analysis of cross-sectional and prospective cohort studies was conducted to assess the associations between total dairy consumption and its different subtypes with the prevalence and incidence of overweight, obesity, and overweight/obesity in children and adolescents. A literature search was conducted in Medline through PUBMED and Cochrane Library databases until October 18, 2021. Articles reporting the risk estimates as odd ratios (OR), risk ratios (RR), or hazard ratios and their corresponding 95% confidence interval (CI) for the association between dairy product consumption and the risk of overweight and/or obesity were included. In the meta-analysis from cross-sectional studies, results showed an inverse association between total dairy consumption and obesity prevalence (OR (95% CI): 0.66 (0.48-0.91). No significant associations were found between milk or yogurt and obesity prevalence risk. Regarding prospective studies, total milk consumption was positively associated with overweight prevalence (OR (95% CI): 1.13 (1.01-1.26)) and incidence (RR (95%CI): 1.17 (1.01-1.35)) risk. Evidence from pooled analysis of cross-sectional studies suggested an inverse association between total dairy consumption and obesity. However, there is limited and no conclusive evidence to confirm an inverse relationship from pooled analysis of prospective studies in children and adolescents.

摘要

我们进行了一项横断面和前瞻性队列研究的系统评价和荟萃分析,以评估儿童和青少年的总乳制品摄入量及其不同亚型与超重、肥胖以及超重/肥胖患病率和发病率之间的关联。截至2021年10月18日,我们通过PUBMED和Cochrane图书馆数据库在Medline中进行了文献检索。纳入了报告乳制品消费与超重和/或肥胖风险之间关联的风险估计值,如比值比(OR)、风险比(RR)或风险率及其相应的95%置信区间(CI)的文章。在横断面研究的荟萃分析中,结果显示总乳制品摄入量与肥胖患病率之间存在负相关(OR(95%CI):0.66(0.48 - 0.91))。未发现牛奶或酸奶与肥胖患病率风险之间存在显著关联。关于前瞻性研究,总牛奶摄入量与超重患病率(OR(95%CI):1.13(1.01 - 1.26))和发病率(RR(95%CI):1.17(1.01 - 1.35))风险呈正相关。横断面研究的汇总分析证据表明总乳制品摄入量与肥胖之间存在负相关。然而,从儿童和青少年前瞻性研究的汇总分析中,证实这种负相关关系的证据有限且没有定论。

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