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Pertussis toxin blocks angiotensin II-induced calcium influx but not inositol trisphosphate production in adrenal glomerulosa cell.

作者信息

Kojima I, Shibata H, Ogata E

出版信息

FEBS Lett. 1986 Aug 18;204(2):347-51. doi: 10.1016/0014-5793(86)80841-9.

DOI:10.1016/0014-5793(86)80841-9
PMID:3488233
Abstract

Involvement of GTP-binding proteins in angiotensin II-induced mobilization of calcium has been examined in adrenal glomerulosa cells by using pertussis toxin. Pretreatment of glomerulosa cells with pertussis toxin abolishes angiotensin II-induced calcium influx without blocking inositol trisphosphate production. These results suggest a role of the pertussis toxin-sensitive GTP-binding protein in transducing angiotensin II-receptor occupancy into opening of calcium channel.

摘要

相似文献

1
Pertussis toxin blocks angiotensin II-induced calcium influx but not inositol trisphosphate production in adrenal glomerulosa cell.
FEBS Lett. 1986 Aug 18;204(2):347-51. doi: 10.1016/0014-5793(86)80841-9.
2
Angiotensin II and guanine nucleotides stimulate formation of inositol 1,4,5-trisphosphate and its metabolites in permeabilized adrenal glomerulosa cells.血管紧张素II和鸟嘌呤核苷酸刺激通透化肾上腺球状带细胞中肌醇1,4,5-三磷酸及其代谢产物的形成。
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3
The role of guanyl nucleotide binding proteins in the formation of inositol phosphates in adrenal glomerulosa cells.鸟苷酸结合蛋白在肾上腺球状带细胞中肌醇磷酸形成过程中的作用。
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4
Direct evidence for involvement of a guanine nucleotide-binding protein in chemotactic peptide-stimulated formation of inositol bisphosphate and trisphosphate in differentiated human leukemic (HL-60) cells. Reconstitution with Gi or Go of the plasma membranes ADP-ribosylated by pertussis toxin.鸟嘌呤核苷酸结合蛋白参与分化的人白血病（HL-60）细胞中趋化肽刺激的肌醇二磷酸和三磷酸形成的直接证据。用百日咳毒素ADP-核糖基化的质膜与Gi或Go进行重组。
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5
Effects of islet-activating protein on the catecholamine release, Ca2+ mobilization and inositol trisphosphate formation in cultured adrenal chromaffin cells.
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6
Angiotensin II and dopamine modulate both cAMP and inositol phosphate productions in anterior pituitary cells. Involvement in prolactin secretion.
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Bradykinin stimulation of inositol phosphate and calcium responses in insensitive to pertussis toxin in NG115-401L neuronal cells.缓激肽刺激NG115 - 401L神经元细胞中肌醇磷酸和钙反应，对百日咳毒素不敏感。
Biochem Biophys Res Commun. 1987 Oct 14;148(1):412-6. doi: 10.1016/0006-291x(87)91126-0.
8
Epidermal growth factor and angiotensin II stimulate formation of inositol 1,4,5- and inositol 1,3,4-trisphosphate in hepatocytes. Differential inhibition by pertussis toxin and phorbol 12-myristate 13-acetate.表皮生长因子和血管紧张素II刺激肝细胞中肌醇1,4,5-三磷酸和肌醇1,3,4-三磷酸的形成。百日咳毒素和佛波醇12-肉豆蔻酸酯13-乙酸酯的差异抑制作用。
J Biol Chem. 1987 Dec 25;262(36):17285-93.
9
An islet activating protein-sensitive G protein is involved in dopamine inhibition of angiotensin and thyrotropin-releasing hormone-stimulated inositol phosphate production in anterior pituitary cells.一种对胰岛激活蛋白敏感的G蛋白参与多巴胺对垂体前叶细胞中血管紧张素和促甲状腺激素释放激素刺激的肌醇磷酸生成的抑制作用。
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10
Bradykinin-induced generation of inositol 1,4,5-trisphosphate in fibroblasts and neuroblastoma cells: effect of pertussis toxin, extracellular calcium, and down-regulation of protein kinase C.缓激肽诱导成纤维细胞和神经母细胞瘤细胞中肌醇1,4,5 -三磷酸的生成：百日咳毒素、细胞外钙及蛋白激酶C下调的影响
Biochem Biophys Res Commun. 1988 Dec 30;157(3):1429-35. doi: 10.1016/s0006-291x(88)81035-0.

引用本文的文献

1
Bidirectional modulation of exocytosis by angiotensin II involves multiple G-protein-regulated transduction pathways in chromaffin cells.血管紧张素II对胞吐作用的双向调节涉及嗜铬细胞中多种G蛋白调节的转导途径。
J Neurosci. 2000 Jul 1;20(13):4776-85. doi: 10.1523/JNEUROSCI.20-13-04776.2000.
2
Evidence that a pertussis-toxin-sensitive substrate is involved in the stimulation by epidermal growth factor and vasopressin of plasma-membrane Ca2+ inflow in hepatocytes.有证据表明，一种对百日咳毒素敏感的底物参与了表皮生长因子和血管加压素对肝细胞质膜Ca2+内流的刺激作用。
Biochem J. 1987 Dec 15;248(3):911-8. doi: 10.1042/bj2480911.
3
Cholera-toxin and corticotropin modulation of inositol phosphate accumulation induced by vasopressin and angiotensin II in rat glomerulosa cells.
霍乱毒素和促肾上腺皮质激素对血管加压素和血管紧张素II诱导的大鼠球状带细胞肌醇磷酸积累的调节作用
Biochem J. 1988 Aug 1;253(3):765-75. doi: 10.1042/bj2530765.
4
Muscarinic receptor regulation of Ca2+ mobilization in a human salivary cell line.毒蕈碱受体对人唾液腺细胞系中钙离子动员的调节作用
Pflugers Arch. 1989 Mar;413(5):505-10. doi: 10.1007/BF00594181.
5
Angiotensin II induces oscillations of intracellular calcium and blocks anomalous inward rectifying potassium current in mouse renal juxtaglomerular cells.血管紧张素II可诱导小鼠肾球旁细胞内钙离子振荡，并阻断内向整流钾电流异常。
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6
[Functional guanine nucleotide-binding proteins in receptor-mediated modulation of voltage-dependent ion channels].[受体介导的电压依赖性离子通道调节中的功能性鸟嘌呤核苷酸结合蛋白]
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7
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Proc Natl Acad Sci U S A. 1988 Dec;85(23):8865-9. doi: 10.1073/pnas.85.23.8865.
8
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