Ji Guixiang, Chen Qi, Ding Zhen, Gu Jie, Guo Min, Shi Lili, Yu Hao, Sun Hong
Nanjing Institute of Environmental Sciences, Ministry of Ecology and Environment, Nanjing, 210042, China.
Jiangsu Provincial Centre for Disease Control and Prevention, Nanjing, 210009, China.
Environ Pollut. 2022 Feb 1;294:118635. doi: 10.1016/j.envpol.2021.118635. Epub 2021 Dec 6.
Studies on the human body burden of dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) in populations around municipal solid waste incinerators (MSWIs) in China are limited. The objective of this study was to assess the potential adverse health effects of an 8-year MSWI on the surrounding population and identify possible exposure pathways. We hypothesized that the MSWI would result in different environmental impacts and population health outcomes between upwind and downwind of its 3 km vicinity. We conducted a 10-year retrospective mortality survey on the population surrounding the MSWI. Then, we selected 50 residents aged 50 years or older on each of the upwind and downwind sides of MSWI to test serum PCDD/Fs. Meanwhile, environmental and food exposures to PCDD/Fs were tested for selected residents. The age-adjusted mortality rates were significantly higher for residents downwind than upwind, but no significant difference was found in the standardized mortality ratio before and after the MSWI operation. The toxic equivalents (TEQ) and major congeners of PCDD/Fs were significantly higher in the sera of the downwind residents than in the upwind. The PCDD/Fs in air, soil, dust, and vegetables on the downwind side were not significantly different from those on the upwind side, but the mean concentrations of PCDD/Fs in downwind hen eggs was significantly higher than those from upwind. In conclusion, downwind residents living within 3 km of the MSWI had higher age-adjusted mortality and serum level of PCDD/Fs than upwind residents. This higher mortality rate among downwind residents was not associated with MSWI. However, the higher levels of PCDD/Fs in downwind hen eggs suggest that the downwind population dioxin exposure was related to their location.
关于中国城市固体废弃物焚烧炉（MSWI）周边人群二噁英和二苯并呋喃（PCDD/Fs）人体负担的研究有限。本研究的目的是评估一座运行8年的MSWI对周边人群潜在的健康不良影响，并确定可能的暴露途径。我们假设，MSWI在其3公里范围内的上风和下风区域会导致不同的环境影响和人群健康结果。我们对MSWI周边人群进行了为期10年的回顾性死亡率调查。然后，我们在MSWI上风和下风两侧各选取50名50岁及以上居民检测血清PCDD/Fs。同时，对选定居民的环境和食物中PCDD/Fs暴露情况进行检测。下风居民的年龄调整死亡率显著高于上风居民，但在MSWI运行前后的标准化死亡比中未发现显著差异。下风居民血清中PCDD/Fs的毒性当量（TEQ）和主要同系物显著高于上风居民。下风侧空气、土壤、灰尘和蔬菜中的PCDD/Fs与上风侧无显著差异，但下风侧鸡蛋中PCDD/Fs的平均浓度显著高于上风侧。总之，居住在MSWI 3公里范围内下风区域的居民比上风区域居民有更高的年龄调整死亡率和血清PCDD/Fs水平。下风居民中较高的死亡率与MSWI无关。然而，下风侧鸡蛋中较高水平的PCDD/Fs表明下风区域人群的二噁英暴露与他们的位置有关。
