国际糖尿病联盟糖尿病地图集：妊娠合并糖尿病的患病率——2010-2020 年发表的研究的系统评价和荟萃分析。
IDF Diabetes Atlas: The prevalence of pre-existing diabetes in pregnancy - A systematic reviewand meta-analysis of studies published during 2010-2020.
机构信息
Department of Population Medicine, College of medicine, QU Health, Qatar University, Doha, Qatar.
Department of Psychiatry, University of Oxford, Oxford, UK.
出版信息
Diabetes Res Clin Pract. 2022 Jan;183:109049. doi: 10.1016/j.diabres.2021.109049. Epub 2021 Dec 6.
OBJECTIVES
To estimate the prevalence of pre-existing diabetes in pregnancy from studies published during 2010-2020.
METHODS
We searched PubMed, CINAHL, Scopus and other sources for relevant data sources. The prevalence of overall pre-existing, type 1 and type 2 diabetes, by country, region and period of study was synthesised from included studies using the inverse-variance heterogeneity model and the Freeman-Tukey transformation. Heterogeneity was assessed using the I statistic and publication bias using funnel plots.
RESULTS
We identified 2479 records, of which 42 data sources with a total of 78 943 376 women, met the eligibility criteria. The included studies were from 17 countries in North America, Europe, the Middle East and North Africa, Australasia, Asia and Africa. The lowest prevalence was in Europe (0.5%, 95 %CI 0.4-0.7) and the highest in the Middle East and North Africa (2.4%, 95 %CI 1.5-3.1). The prevalence of pre-existing diabetes doubled from 0.5% (95 %CI 0.1-1.0) to 1.0% (95 %CI 0.6-1.5) during the period 1990-2020. The pooled prevalences of pre-existing type 1 and type 2 diabetes were 0.3% (95 %CI 0.2-0.4) and 0.2% (95 %CI 0.0-0.9) respectively.
CONCLUSION
While the prevalence of pre-existing diabetes in pregnancy is low, it has doubled from 1990 to 2020.
目的
评估 2010 年至 2020 年期间发表的研究中妊娠合并糖尿病的患病率。
方法
我们检索了 PubMed、CINAHL、Scopus 和其他来源以获取相关数据。使用逆方差异质性模型和 Freeman-Tukey 变换，从纳入的研究中综合了按国家、地区和研究时间段计算的总体妊娠合并糖尿病、1 型糖尿病和 2 型糖尿病的患病率。使用 I 统计量评估异质性，并使用漏斗图评估发表偏倚。
结果
我们共检索到 2479 条记录，其中 42 条数据来源（共纳入 78943376 名女性）符合纳入标准。纳入的研究来自北美、欧洲、中东和北非、澳大拉西亚、亚洲和非洲的 17 个国家。患病率最低的地区为欧洲（0.5%，95%CI 0.4-0.7），最高的地区为中东和北非（2.4%，95%CI 1.5-3.1）。妊娠合并糖尿病的患病率从 1990 年的 0.5%（95%CI 0.1-1.0）增加到 2020 年的 1.0%（95%CI 0.6-1.5），增加了一倍。妊娠合并 1 型和 2 型糖尿病的患病率分别为 0.3%（95%CI 0.2-0.4）和 0.2%（95%CI 0.0-0.9）。
结论
尽管妊娠合并糖尿病的患病率较低，但自 1990 年以来增加了一倍。
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