Bramati Patricia, Bruera Eduardo
Department of Palliative Care, Rehabilitation and Integrative Medicine, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 1414, Houston, TX 77030, USA.
Cancers (Basel). 2021 Nov 23;13(23):5893. doi: 10.3390/cancers13235893.
Delirium, a widespread neuropsychiatric disorder in patients with terminal diseases, is associated with increased morbidity and mortality, profoundly impacting patients, their families, and caregivers. Although frequently missed, the effective recognition of delirium demands attention and commitment. Reversibility is frequently not achievable. Non-pharmacological and pharmacological interventions are commonly used but largely unproven. Palliative sedation, although controversial, should be considered for refractory delirium. Psychological assistance should be available to patients and their families at all times.
谵妄是绝症患者中一种普遍存在的神经精神障碍,与发病率和死亡率的增加相关,对患者及其家人和护理人员产生深远影响。尽管常常被漏诊,但有效识别谵妄需要关注和投入。谵妄通常无法逆转。非药物和药物干预措施常用,但大多未经证实。姑息性镇静尽管存在争议,但对于难治性谵妄应予以考虑。应随时为患者及其家人提供心理援助。