Department of Medicine, Surgery and Neuroscience, University of Siena, 53100 Siena, Italy.
PhD School of Applied Medical-Surgical Sciences, University of Rome "Tor Vergata", 00133 Rome, Italy.
Int J Environ Res Public Health. 2021 Dec 4;18(23):12802. doi: 10.3390/ijerph182312802.
many patients who struggle to lose weight are unable to cut down certain ultra-processed, refined types of food with a high glycemic index. This condition is linked to responses similar to addiction that lead to overeating. A very-low-calorie ketogenic diet (VLCKD) with adequate protein intake could be considered a valid dietary approach. The aim of the present study was to evaluate the feasibility of a VLCKD in women with binge eating and/or food addiction symptoms.
subjects diagnosed with binge eating and/or food addiction symptoms (measured with the Binge Eating Scale and the Yale Food Addiction Scale 2.0) were asked to follow a VLCKD with protein replacement for 5-7 weeks (T1) and a low-calorie diet for 11-21 weeks (T2). Self-reported food addiction and binge eating symptoms and body composition were tested at T0 (baseline) and at the end of each diet (T1 and T2 respectively); Results: five women were included in the study. Mean age was 36.4 years (SEM = 4.95) and mean BMI was 31.16 (SEM = 0.91). At T0, two cases of severe food addiction, one case of mild food addiction, one case of binge eating with severe food addiction, and one case of binge eating were recorded. Weight loss was recorded at both T1 and T2 (ranging from 4.8% to 11.6% of the initial body weight at T1 and from 7.3% to 12.8% at T2). No case of food addiction and/or binge eating symptoms was recorded at T2. Muscle mass was preserved.
recent findings have highlighted the potential therapeutic role of ketogenic diets for the treatment of addiction to high-calorie, ultra-processed and high-glycemic food. Our pilot study demonstrates the feasibility of a ketogenic diet in women with addictive-like eating disorders seeking to lose weight.
许多试图减肥的患者无法减少某些超高加工、精制且血糖指数高的食物。这种情况与类似成瘾的反应有关,导致暴饮暴食。摄入足够蛋白质的极低卡路里生酮饮食(VLCKD)可被视为一种有效的饮食方法。本研究旨在评估 VLCKD 对有暴食和/或食物成瘾症状的女性的可行性。
被诊断为暴食和/或食物成瘾症状的受试者(通过暴食量表和耶鲁食物成瘾量表 2.0 测量)被要求遵循 VLCKD 加蛋白质替代物 5-7 周(T1)和低卡路里饮食 11-21 周(T2)。在 T0(基线)和每个饮食结束时(分别为 T1 和 T2)测试自我报告的食物成瘾和暴食症状以及身体成分;结果:本研究纳入了 5 名女性。平均年龄为 36.4 岁(SEM = 4.95),平均 BMI 为 31.16(SEM = 0.91)。在 T0 时,记录了 2 例严重食物成瘾、1 例轻度食物成瘾、1 例暴食伴严重食物成瘾和 1 例暴食。在 T1 和 T2 时均记录了体重减轻(T1 时初始体重的 4.8%至 11.6%,T2 时为 7.3%至 12.8%)。在 T2 时没有记录到食物成瘾和/或暴食症状。肌肉质量得以保留。
最近的研究结果强调了生酮饮食治疗高热量、超高加工和高血糖食物成瘾的潜在治疗作用。我们的初步研究表明,生酮饮食对寻求减肥的有类似成瘾饮食障碍的女性是可行的。