Eating Disorders Research Unit, Universidad Católica de Murcia, Campus de Guadalupe, Guadalupe, 30107, Murcia, Spain.
Department of Biochemistry and Molecular Biology II, Institute of Nutrition and Food Technology, Center for Biomedical Research (CIBM), University of Granada, Granada, Spain.
Obes Surg. 2024 Sep;34(9):3475-3492. doi: 10.1007/s11695-024-07107-6. Epub 2024 Jul 29.
There are different treatments for food addiction (FA) symptomatology, but a comprehensive review with a meta-analysis to determine the most effective intervention is lacking. The aim of this review is to investigate the efficacy of pharmacological, behavioral, and bariatric-metabolic surgical interventions in reducing FA symptomatology. Meta-analyses including 15 studies in adults showed a significantly positive effect (std mean difference in FA symptoms before vs after intervention 0.72 (0.58-0.95)), with bariatric-metabolic surgical interventions showing the highest efficacy in improving FA symptoms (1.17 (0.58-1.76) before vs after intervention). The existing evidence suggests a beneficial effect of bariatric-metabolic surgical, pharmacological, and behavioral interventions, in that order, on FA symptomatology in people with overweight/obesity. Weight loss and behavioral and lifestyle changes after surgery may be determinants in improving FA symptomatology.
针对食物成瘾（FA）症状，有不同的治疗方法，但缺乏全面的综述和荟萃分析来确定最有效的干预措施。本综述的目的是研究药物治疗、行为治疗和减重代谢手术干预在减轻 FA 症状方面的疗效。纳入了 15 项成人研究的荟萃分析显示，这些干预措施具有显著的积极效果（FA 症状在干预前后的标准均数差值为 0.72（0.58-0.95）），其中减重代谢手术干预在改善 FA 症状方面效果最高（干预前后差值为 1.17（0.58-1.76））。现有证据表明，在超重/肥胖人群中，减重代谢手术、药物治疗和行为治疗干预对 FA 症状均有有益的影响，其效果依次递减。手术后的体重减轻以及行为和生活方式的改变可能是改善 FA 症状的决定因素。
