在无胸腺（裸）小鼠、B细胞缺陷（xid）小鼠和脾切除小鼠中诱导早期内毒素耐受性。
Induction of early-phase endotoxin tolerance in athymic (nude) mice, B-cell-deficient (xid) mice, and splenectomized mice.
作者信息
Madonna G S, Vogel S N
出版信息
Infect Immun. 1986 Sep;53(3):707-10. doi: 10.1128/iai.53.3.707-710.1986.
Abstract
Early-phase endotoxin tolerance was inducible in mice which were T cell deficient (nude), B cell deficient (xid), or asplenic, which suggests that these lymphoid cell subsets and the spleen do not contribute significantly to the induction of acquired lipopolysaccharide hyporesponsiveness. C3H/HeJ mice did not exhibit the hematopoietic changes observed in mice made endotoxin tolerant, which suggests that multiple mechanisms may underlie lipopolysaccharide hyporesponsiveness.
摘要
在T细胞缺陷（裸鼠）、B细胞缺陷（xid小鼠）或无脾的小鼠中可诱导早期内毒素耐受，这表明这些淋巴细胞亚群和脾脏对获得性脂多糖低反应性的诱导没有显著贡献。C3H/HeJ小鼠没有表现出在内毒素耐受小鼠中观察到的造血变化，这表明脂多糖低反应性可能有多种机制。
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本文引用的文献
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