Areekul S, Muangman V, Bohkerd C, Saenghirun C
Southeast Asian J Trop Med Public Health. 1978 Sep;9(3):427-32.
An 8-year-old boy was admitted into the hospital with symptoms of anuria after consumption of 12 djenkol beans. Laparotomy showed a urethral calculus, size 2.0 x 0.4 cm, which was found to contain djenkolic acid 65 gm/100 gm stone with a small amount of protein, sodium, potassium and uric acid. This calculus contained no calcium, magnesium, phosphorus, ammonium salt, oxalate, carbonate, cystine and fibrin. The solubility of L-djenkolic acid in urine at 37 degrees C was found to be pH dependent, i.e., the higher the pH, the increase in solubility of djenkolic acid. D-pencillamine also showed similar effect, increasing the solubility of L-djenkolic acid in the urine at pH 5.7 in vitro. The cause and mechanism of formation of djenkolic acid crystals and calculi were discussed.
一名8岁男孩在食用12颗节豆后因无尿症状入院。剖腹探查显示尿道结石，大小为2.0×0.4厘米，发现结石含65克/100克结石的詹氏酸，还有少量蛋白质、钠、钾和尿酸。该结石不含钙、镁、磷、铵盐、草酸盐、碳酸盐、胱氨酸和纤维蛋白。发现L-詹氏酸在37摄氏度尿液中的溶解度取决于pH值，即pH值越高，詹氏酸的溶解度增加。D-青霉胺也显示出类似效果，在体外pH值为5.7时增加L-詹氏酸在尿液中的溶解度。文中讨论了詹氏酸晶体和结石形成的原因及机制。
