Sethi Jasmine, Anandh Urmila, Jha Vivekanand
Department of Nephrology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Department of Nephrology, Amrita Institute of Medical Sciences and Research Centre, Faridabad, India.
Indian J Nephrol. 2025 May-Jun;35(3):335-342. doi: 10.25259/IJN_321_2024. Epub 2024 Oct 24.
Traditional medicine refers to a diverse range of health and healing practices used by Indigenous peoples that incorporate plants, animals, and the spiritual realm for the diagnosis and treatment of illness or maintenance of health and well-being. While these practices hold significant cultural value, there is growing evidence of potential nephrotoxicity associated with some traditional indigenous medicines (TIMs). In this review, we explore the various clinical manifestations of nephrotoxicity induced by TIMs. Nephrotoxicity can result from various factors, including the intrinsic toxicity of certain herbs, contamination with heavy metals, inappropriate dosages, and interaction with conventional medications. This review highlights the importance of monitoring kidney function in patients using TIMs and calls for increased awareness and regulation to ensure the safe use of these traditional therapies.
传统医学是指原住民使用的多种健康和治疗方法，这些方法结合了植物、动物和精神领域来诊断和治疗疾病或维持健康与幸福。虽然这些做法具有重要的文化价值，但越来越多的证据表明，一些传统本土药物（TIMs）存在潜在的肾毒性。在本综述中，我们探讨了TIMs引起的肾毒性的各种临床表现。肾毒性可能由多种因素引起，包括某些草药的内在毒性、重金属污染、不适当的剂量以及与传统药物的相互作用。本综述强调了对使用TIMs的患者进行肾功能监测的重要性，并呼吁提高认识和加强监管，以确保这些传统疗法的安全使用。
