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570 例机器人全内镜冠状动脉旁路移植术:两个时代吻合技术的影响。

Robotic Total Endoscopic Coronary Bypass in 570 Patients: Impact of Anastomotic Technique in Two Eras.

机构信息

Department of Cardiothoracic Surgery, University of Chicago Medicine, Chicago, Illinois.

Department of Cardiothoracic Surgery, University of Chicago Medicine, Chicago, Illinois.

出版信息

Ann Thorac Surg. 2022 Aug;114(2):476-482. doi: 10.1016/j.athoracsur.2021.10.049. Epub 2021 Dec 7.

Abstract

BACKGROUND

In coronary artery bypass grafting, including robotic off-pump totally endoscopic coronary artery bypass (TECAB), the anastomotic technique is the most critical part of the procedure. We reviewed results in 570 patients over a 7-year period and compared outcomes between two eras based on predominant anastomotic technique: connectors vs running suture.

METHODS

Between July 2013 and December 2020, 570 patients underwent off-pump TECAB: group 1 consisting of 378 patients, from July 2013 to August 2018, using predominantly the C-Port Flex A distal anastomotic stapler (Aesculap); and group 2 consisting of 192 patients, from September 2018 to December 2020, using predominantly a sutured technique (7-0 Pronova; Johnson & Johnson). Retrospective analysis of clinical outcomes was performed.

RESULTS

Off-pump TECAB was completed in 98.8% (563 of 570 patients) with an observed/expected mortality of 0.6% (6 of 570 patients). The anastomotic device was used in 89% of 626 grafts in group 1 and only 11% of 305 grafts in group 2 (P = .001). There were no differences in multivessel TECAB (57% vs 53%; P = .331) or bilateral internal thoracic artery use (50% vs 43%; P = .127) in group 1 vs group 2, respectively. Operative time was shorter in group 1 (242 ± 84 vs 273 ± 88 minutes; P < .001). Early clinical outcomes were similar between groups, except for hospital stay, which was longer in group 1 (2.9 vs 2.3 days; P < .001). Graft patency was similar (98% vs 95%; P = .295) in group 1 vs group 2, respectively.

CONCLUSIONS

Changing the predominant approach from stapled anastomosis to a sutured technique during robotic TECAB resulted in longer operative times. Both approaches led to excellent outcomes, including graft patency. The shorter operative times conferred by using staplers may flatten the learning curve and facilitate broader adoption of TECAB.

摘要

背景

在冠状动脉旁路移植术中,包括机器人非体外循环全内镜冠状动脉旁路移植术(TECAB),吻合技术是手术中最关键的部分。我们回顾了 7 年内 570 例患者的结果,并根据主要吻合技术将结果在两个时代进行了比较:连接器与连续缝合。

方法

2013 年 7 月至 2020 年 12 月,570 例患者接受了非体外循环 TECAB 手术:第 1 组 378 例,2013 年 7 月至 2018 年 8 月,主要使用 C-Port Flex A 远端吻合器(捷迈邦美);第 2 组 192 例,2018 年 9 月至 2020 年 12 月,主要使用缝合技术(7-0 Pronova;强生)。对临床结果进行了回顾性分析。

结果

570 例患者中有 98.8%(563 例)完成了非体外循环 TECAB,观察/预期死亡率为 0.6%(6 例)。在第 1 组的 626 个移植物中,吻合器的使用率为 89%,而在第 2 组的 305 个移植物中,吻合器的使用率仅为 11%(P=0.001)。第 1 组与第 2 组多血管 TECAB(57%对 53%;P=0.331)或双侧内乳动脉使用(50%对 43%;P=0.127)均无差异。第 1 组的手术时间较短(242±84 分钟对 273±88 分钟;P<0.001)。两组的早期临床结果相似,除了第 1 组的住院时间较长(2.9 天对 2.3 天;P<0.001)。第 1 组与第 2 组的移植物通畅率相似(98%对 95%;P=0.295)。

结论

在机器人 TECAB 中,将主要吻合方法从吻合器吻合改为缝合技术,导致手术时间延长。这两种方法都取得了极好的结果,包括移植物通畅率。使用吻合器可缩短手术时间,可能使学习曲线变平,并促进 TECAB 的更广泛应用。

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