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美国退伍军人的酒精中毒过量死亡。

Alcohol-involved overdose deaths in US veterans.

机构信息

VA Center for Clinical Management Research (CCMR), VA Ann Arbor Healthcare System, Building 16 2800 Plymouth Rd, Ann Arbor, MI 48109, United States; Addiction Center, Department of Psychiatry, University of Michigan, 4250 Plymouth Rd, Ann Arbor, MI 48109, United States; University of Michigan Injury Prevention Center, 2800 Plymouth Road, Suite B10-G080, Ann Arbor, MI 48109-2800, United States.

Addiction Center, Department of Psychiatry, University of Michigan, 4250 Plymouth Rd, Ann Arbor, MI 48109, United States; University of Michigan Injury Prevention Center, 2800 Plymouth Road, Suite B10-G080, Ann Arbor, MI 48109-2800, United States.

出版信息

Drug Alcohol Depend. 2022 Jan 1;230:109196. doi: 10.1016/j.drugalcdep.2021.109196. Epub 2021 Nov 26.

Abstract

BACKGROUND

Alcohol-involved overdose deaths are increasing and often occur with other substances but have been minimally studied compared to other causes of overdose.

METHODS

We used national Veterans Health Administration (VHA) records linked to National Death Index data from 2012 to 2018 to examine trends in alcohol-related overdose mortality. Patient characteristics and treatment receipt were compared across categories of alcohol overdose deaths (alcohol-only, alcohol+opioids which may include additional substances, and alcohol+other substances without opioids).

RESULTS

From 2012-2018, 2421 Veterans died from an alcohol-involved overdose (alcohol-only: 868, alcohol+opioids: 1269, alcohol+other substances: 284). The alcohol-involved overdose rate increased 57% during this period. Compared to those who died of an alcohol-only overdose, Veterans who died from alcohol+opioids and alcohol+other substances were more likely Black or Hispanic, and to have an opioid use disorder, but less likely to live in rural areas or to be diagnosed with alcohol use disorder (AUD). Only 32.5% of those who died from alcohol-involved overdose received treatment in a substance use disorder clinic in the year preceding death, compared to 65.1% seen in mental health and 85.7% in primary care. Only 9.5% of Veterans who died from alcohol overdose received medication treatment for AUD and 24.8% received psychotherapy for AUD in the year preceding death.

CONCLUSIONS

Alcohol overdose is increasing primarily related to overdoses involving opioids and other substances. Most patients did not receive any effective medication or psychotherapy treatments for AUD, suggesting further need to identify those at risk and to target treatment for this vulnerable group in healthcare settings.

摘要

背景

涉及酒精的过量用药死亡人数正在增加,且通常与其他物质同时发生,但与其他过量用药原因相比,此类死亡的研究极少。

方法

我们使用 2012 年至 2018 年期间全国退伍军人健康管理局(VHA)记录与国家死亡指数数据进行关联,以检查与酒精相关的过量用药死亡趋势。我们比较了酒精过量用药死亡(仅酒精、可能包括其他物质的酒精+阿片类药物,以及无阿片类药物的酒精+其他物质)各分类的患者特征和治疗情况。

结果

2012 年至 2018 年期间,有 2421 名退伍军人死于酒精相关的过量用药(仅酒精:868 人,酒精+阿片类药物:1269 人,酒精+其他物质:284 人)。在此期间,酒精相关的过量用药率增加了 57%。与死于仅酒精过量用药的患者相比,死于酒精+阿片类药物和酒精+其他物质的退伍军人更有可能是黑人和西班牙裔,且更有可能患有阿片类药物使用障碍,但更不可能居住在农村地区或被诊断为酒精使用障碍(AUD)。在死亡前一年,仅有 32.5%死于酒精相关过量用药的患者在物质使用障碍诊所接受治疗,而在心理健康和初级保健中分别有 65.1%和 85.7%的患者接受治疗。在死亡前一年,仅有 9.5%的酒精过量用药死亡的退伍军人接受 AUD 药物治疗,24.8%接受 AUD 心理治疗。

结论

酒精过量用药的增加主要与涉及阿片类药物和其他物质的过量用药有关。大多数患者没有接受 AUD 的任何有效药物或心理治疗,这表明需要进一步确定高危人群,并在医疗保健环境中针对这一脆弱群体开展治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da7d/8714700/bd094fb3943b/nihms-1764623-f0001.jpg

相似文献

1
Alcohol-involved overdose deaths in US veterans.美国退伍军人的酒精中毒过量死亡。
Drug Alcohol Depend. 2022 Jan 1;230:109196. doi: 10.1016/j.drugalcdep.2021.109196. Epub 2021 Nov 26.

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