先天性巨细胞病毒感染的前庭和姿势障碍。
Vestibular and postural impairment in congenital Cytomegalovirus infection.
机构信息
ENT and Audiology Department, University Hospital of Ferrara, A. Moro 8, loc Cona, Ferrara, 44124, Italy.
Institute of Sensory Organs, 1 Mokra Street, 05-830, Nadarzyn/Kajetany, Poland; Institute of Physiology and Pathology of Hearing, 10 Mochnackiego Street, 02-042, Warsaw, Poland.
出版信息
Int J Pediatr Otorhinolaryngol. 2022 Jan;152:111005. doi: 10.1016/j.ijporl.2021.111005. Epub 2021 Dec 7.
OBJECTIVES
To describe the vestibular and postural impairment related to the congenital Cytomegalovirus infection (cCMV), including the inner ear damages CMV-induced.
METHODS
A PRISMA systematic review was performed, with the PubMed, Embase, and Cinahl databases searched from inception through to March 2021; after the application of inclusion and exclusion criteria a total of 12 papers were included in this review.
RESULTS
Vestibular and postural disorders have been reported in cCMV children, with a high variability of clinical manifestation. Presently, the available reported data on vestibular and postural impairment in cCMV children differ in terms of the sample size and the features of the studied populations.
CONCLUSION
At present, the vestibular and postural impairment in cCMV cases is underestimated; a complete vestibular assessment, a follow-up and management of all children affected by cCMV or, at least, of all cCMV patients showing sensorineural hearing loss, is recommended.
目的
描述先天性巨细胞病毒感染（cCMV）相关的前庭和姿势障碍，包括 CMV 引起的内耳损伤。
方法
进行了 PRISMA 系统评价，从开始到 2021 年 3 月，检索了 PubMed、Embase 和 Cinahl 数据库；应用纳入和排除标准后，共有 12 篇论文纳入本综述。
结果
cCMV 儿童存在前庭和姿势障碍，临床表现具有高度变异性。目前，关于 cCMV 儿童前庭和姿势障碍的现有报告数据在样本量和研究人群特征方面存在差异。
结论
目前，cCMV 病例的前庭和姿势障碍被低估；建议对所有受 cCMV 影响的儿童，或至少对所有出现感觉神经性听力损失的 cCMV 患者进行全面的前庭评估、随访和管理。
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