在拉伸的青蛙肌肉单皮纤维中，晶格收缩随静息张力增加而发生。
Lattice shrinkage with increasing resting tension in stretched, single skinned fibers of frog muscle.
作者信息
Higuchi H, Umazume Y
出版信息
Biophys J. 1986 Sep;50(3):385-9. doi: 10.1016/S0006-3495(86)83474-9.
Abstract
The 1,0 lattice spacing d1,0 in chemically and mechanically skinned single fibers of frog muscle was measured at various sarcomere lengths, L, in the range from L = 2.1 to 6.0 microns by an x-ray diffraction method. In chemically skinned fibers, d1,0 decreased with a similar slope to that of mechanically skinned fibers up to L congruent to 3 microns, but beyond this point d1,0 steeply decreased with further stretching. This steep decrease in d1,0 could be ascribed mainly to an increase in the compressing force associated with the longitudinal extension of a remnant of the sarcolemma. In mechanically skinned fibers, the gradual decrease in d1,0 continued beyond filament overlap (L greater than or equal to 3.5 microns) and was highly proportional to a resting tension. This decrease in d1,0 at L greater than or equal to 3.5 microns could be ascribed to an increase in the force exerted by lateral elastic components, which is proportional to the longitudinal resting tension. A conceptual model is proposed of a network structure of elastic components in a sarcomere.
摘要
通过X射线衍射法，在2.1至6.0微米的不同肌节长度L范围内，测量了青蛙肌肉化学去膜和机械去膜单纤维中的1,0晶格间距d1,0。在化学去膜纤维中，直到L约为3微米时，d1,0以与机械去膜纤维相似的斜率下降，但超过这一点后，随着进一步拉伸，d1,0急剧下降。d1,0的这种急剧下降主要可归因于与肌膜残余物纵向延伸相关的压缩力增加。在机械去膜纤维中，d1,0的逐渐下降在细丝重叠之后（L大于或等于3.5微米）仍继续，并且与静息张力高度成比例。在L大于或等于3.5微米时d1,0的这种下降可归因于横向弹性成分施加的力增加，该力与纵向静息张力成比例。提出了一个肌节中弹性成分网络结构的概念模型。
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本文引用的文献
1
THE MAXIMUM SARCOMERE LENGTH FOR CONTRACTION OF ISOLATED MYOFIBRILS.分离肌原纤维收缩的最大肌节长度。
J Physiol. 1964 Jan;170(1):110-23. doi: 10.1113/jphysiol.1964.sp007317.
2
A SMALL-ANGLE OPTICALLY FOCUSING X-RAY DIFFRACTION CAMERA IN BIOLOGICAL RESEARCH. I.生物研究中的一种小角度光学聚焦X射线衍射相机。I.
J Ultrastruct Res. 1963 Aug;49:166-70. doi: 10.1016/s0022-5320(63)80044-1.
3
X-ray analysis and the problem of muscle.X射线分析与肌肉问题。
Proc R Soc Lond B Biol Sci. 1953 Mar 11;141(902):59-62. doi: 10.1098/rspb.1953.0017.
4
X-ray diffraction observations of chemically skinned frog skeletal muscle processed by an improved method.采用改进方法处理的化学去膜青蛙骨骼肌的X射线衍射观察。
Biophys J. 1980 Apr;30(1):27-40. doi: 10.1016/S0006-3495(80)85074-0.
5
Geometrical factors influencing muscle force development. II. Radial forces.影响肌肉力量发展的几何因素。II. 径向力。
Biophys J. 1980 Apr;30(1):69-77. doi: 10.1016/S0006-3495(80)85077-6.
6
A network of transverse and longitudinal intermediate filaments is associated with sarcomeres of adult vertebrate skeletal muscle.横向和纵向中间丝网络与成年脊椎动物骨骼肌的肌节相关联。
J Cell Biol. 1983 Feb;96(2):562-70. doi: 10.1083/jcb.96.2.562.
7
Connecting filaments, core filaments, and side-struts: a proposal to add three new load-bearing structures to the sliding filament model.连接丝、核心丝和侧支柱：一项关于在肌丝滑行模型中增加三种新的承重结构的提议。
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8
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J Mol Biol. 1984 Feb 15;173(1):15-33. doi: 10.1016/0022-2836(84)90401-7.
9
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J Mechanochem Cell Motil. 1973 May;2(1):83-9.
10
X-ray diffraction studies on skinned single fibres of frog skeletal muscle.对青蛙骨骼肌去表皮单纤维的X射线衍射研究。
J Mol Biol. 1972 Dec 30;72(3):657-69. doi: 10.1016/0022-2836(72)90183-0.
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