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白细胞计数与 COVID-19 感染严重程度的关系。

ASSOCIATION BETWEEN LEUKOCYTES COUNT AND THE SEVERITY OF COVID-19 INFECTION.

机构信息

REPUBLIC OF IRAQ HEALTH, ENVIRONMENT THE STATE COMPANY FOR MARKETING DRUGS AND MEDICAL APPLIANCES, BAGHDAD, IRAQ.

DEPARTMENT OF CLINICAL LABORATORY SCIENCES, COLLEGE OF PHARMACY, MUSTANSIRIYAH UNIVERSITY, BAGHDAD, IRAQ.

出版信息

Wiad Lek. 2021;74(10 pt 1):2417-2422.

Abstract

OBJECTIVE

The aim: To find an association of COVID-19 on different types of leukocytes either count increasing or decreasing.

PATIENTS AND METHODS

Materials and methods: A cross sectional study conducted from October /2020 to January /2021. Eighty patients out of 170 were enrolled in this study, who were attended a private clinic for clinical investigation and a private laboratory for laboratory diagnosis of COVID-19 who were divided into two groups, asymptomatic or mild (group 1), and moderate or severe (group 2). Five milliliter of blood samples were collected from patients with COVD-19 by venipuncture using a syringe for evaluation of different cells.

RESULTS

Results: The current study revealed a significant difference in white blood cells count, neutrophils count, monocytes count, basophils count, and neutrophil to lymphocyte ratio, lymphocyte to monocyte ratio between group 1 and group 2. While lymphocytes, and eosinophil showed no significant difference.

CONCLUSION

Conclusion: The current study concluded that COVID-19 may affect the count of some leukocytes in patient with severe infection.

摘要

目的

寻找 COVID-19 与白细胞计数增加或减少的不同类型之间的关联。

材料和方法

这是一项横断面研究,于 2020 年 10 月至 2021 年 1 月进行。本研究共纳入了 170 名患者中的 80 名,他们在一家私人诊所接受了临床检查,在一家私人实验室进行了 COVID-19 的实验室诊断,这些患者被分为无症状或轻症(第 1 组)和中症或重症(第 2 组)两组。通过静脉穿刺用注射器从 COVID-19 患者采集 5 毫升血样,用于评估不同的细胞。

结果

本研究表明,第 1 组和第 2 组之间的白细胞计数、中性粒细胞计数、单核细胞计数、嗜碱性粒细胞计数和中性粒细胞与淋巴细胞比值、淋巴细胞与单核细胞比值存在显著差异。而淋巴细胞和嗜酸性粒细胞则没有显著差异。

结论

本研究得出结论,COVID-19 可能会影响严重感染患者的某些白细胞计数。

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