IEEE J Biomed Health Inform. 2022 Apr;26(4):1761-1772. doi: 10.1109/JBHI.2021.3134835. Epub 2022 Apr 14.
AI healthcare applications rely on sensitive electronic healthcare records (EHRs) that are scarcely labelled and are often distributed across a network of the symbiont institutions. It is challenging to train the effective machine learning models on such data. In this work, we propose dynamic neural graphs based federated learning framework to address these challenges. The proposed framework extends Reptile, a model agnostic meta-learning (MAML) algorithm, to a federated setting. However, unlike the existing MAML algorithms, this paper proposes a dynamic variant of neural graph learning (NGL) to incorporate unlabelled examples in the supervised training setup. Dynamic NGL computes a meta-learning update by performing supervised learning on a labelled training example while performing metric learning on its labelled or unlabelled neighbourhood. This neighbourhood of a labelled example is established dynamically using local graphs built over the batches of training examples. Each local graph is constructed by comparing the similarity between embedding generated by the current state of the model. The introduction of metric learning on the neighbourhood makes this framework semi-supervised in nature. The experimental results on the publicly available MIMIC-III dataset highlight the effectiveness of the proposed framework for both single and multi-task settings under data decentralisation constraints and limited supervision.
人工智能医疗应用依赖于敏感的电子医疗记录 (EHRs),这些记录几乎没有标记,并且通常分布在共生机构的网络中。在这些数据上训练有效的机器学习模型具有挑战性。在这项工作中,我们提出了基于动态神经图的联邦学习框架来解决这些挑战。所提出的框架将 Reptile(一种与模型无关的元学习 (MAML) 算法)扩展到联邦设置。然而,与现有的 MAML 算法不同,本文提出了神经图学习 (NGL) 的动态变体,以在监督训练设置中纳入未标记的示例。动态 NGL 通过在标记训练示例上执行监督学习,同时在其标记或未标记的邻域上执行度量学习来计算元学习更新。使用在训练示例批次上构建的本地图来动态建立标记示例的邻域。每个本地图都是通过比较当前模型状态生成的嵌入之间的相似性来构建的。在邻域上进行度量学习的引入使该框架具有半监督性质。在公开的 MIMIC-III 数据集上的实验结果突出了该框架在数据去中心化约束和有限监督下的单任务和多任务设置下的有效性。