Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY; Division of Data-Driven and Digital Medicine, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY; Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
Adv Kidney Dis Health. 2023 Jan;30(1):4-16. doi: 10.1053/j.akdh.2022.11.007.
The success of machine learning-based studies is largely subjected to accessing a large amount of data. However, accessing such data is typically not feasible within a single health system/hospital. Although multicenter studies are the most effective way to access a vast amount of data, sharing data outside the institutes involves legal, business, and technical challenges. Federated learning (FL) is a newly proposed machine learning framework for multicenter studies, tackling data-sharing issues across participant institutes. The promise of FL is simple. FL facilitates multicenter studies without losing data access control and allows the construction of a global model by aggregating local models trained from participant institutes. This article reviewed recently published studies that utilized FL in clinical studies with structured medical data. In addition, challenges and open questions in FL in clinical studies with structured medical data were discussed.
基于机器学习的研究的成功在很大程度上取决于能否访问大量数据。然而,在单个医疗系统/医院内部,通常无法访问此类数据。虽然多中心研究是获取大量数据的最有效方法,但在机构之外共享数据涉及法律、商业和技术方面的挑战。联邦学习(FL)是一种新提出的用于多中心研究的机器学习框架,可解决参与者机构之间的数据共享问题。FL 的承诺很简单。FL 允许在不失去数据访问控制的情况下进行多中心研究,并通过汇总来自参与者机构的本地模型来构建全局模型。本文回顾了最近发表的利用 FL 进行结构化医疗数据临床研究的研究。此外,还讨论了在结构化医疗数据的临床研究中使用 FL 所面临的挑战和尚未解决的问题。