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医疗保健领域中基于异构数据视图的知识抽象与过滤联邦学习

Knowledge abstraction and filtering based federated learning over heterogeneous data views in healthcare.

作者信息

Thakur Anshul, Molaei Soheila, Nganjimi Pafue Christy, Liu Fenglin, Soltan Andrew, Schwab Patrick, Branson Kim, Clifton David A

机构信息

Department of Engineering Science, University of Oxford, Oxford, UK.

Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

出版信息

NPJ Digit Med. 2024 Oct 16;7(1):283. doi: 10.1038/s41746-024-01272-9.

Abstract

Robust data privacy regulations hinder the exchange of healthcare data among institutions, crucial for global insights and developing generalised clinical models. Federated learning (FL) is ideal for training global models using datasets from different institutions without compromising privacy. However, disparities in electronic healthcare records (EHRs) lead to inconsistencies in ML-ready data views, making FL challenging without extensive preprocessing and information loss. These differences arise from variations in services, care standards, and record-keeping practices. This paper addresses data view heterogeneity by introducing a knowledge abstraction and filtering-based FL framework that allows FL over heterogeneous data views without manual alignment or information loss. The knowledge abstraction and filtering mechanism maps raw input representations to a unified, semantically rich shared space for effective global model training. Experiments on three healthcare datasets demonstrate the framework's effectiveness in overcoming data view heterogeneity and facilitating information sharing in a federated setup.

摘要

严格的数据隐私法规阻碍了医疗机构之间医疗数据的交换,而这种交换对于获得全球视野和开发通用临床模型至关重要。联邦学习(FL)非常适合使用来自不同机构的数据集训练全局模型,同时又不会损害隐私。然而,电子健康记录(EHR)的差异导致适用于机器学习的数据视图不一致,使得在没有广泛预处理和信息损失的情况下进行联邦学习具有挑战性。这些差异源于服务、护理标准和记录保存实践的不同。本文通过引入基于知识抽象和过滤的联邦学习框架来解决数据视图异构性问题,该框架允许在异构数据视图上进行联邦学习,而无需手动对齐或信息损失。知识抽象和过滤机制将原始输入表示映射到统一的、语义丰富的共享空间,以进行有效的全局模型训练。在三个医疗数据集上进行的实验证明了该框架在克服数据视图异构性和促进联邦设置中的信息共享方面的有效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f8b/11484763/531d4f812983/41746_2024_1272_Fig1_HTML.jpg

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