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Sutureless valves-are we there yet? Evidence from the PERSIST-AVR trial.无缝合瓣膜——我们做到了吗？来自PERSIST-AVR试验的证据。
Indian J Thorac Cardiovasc Surg. 2022 Jan;38(1):108-110. doi: 10.1007/s12055-021-01289-9. Epub 2021 Nov 23.
2
3
Hemodynamic Performance of Sutureless vs. Conventional Bioprostheses for Aortic Valve Replacement: The 1-Year Core-Lab Results of the Randomized PERSIST-AVR Trial.主动脉瓣置换术中无缝合与传统生物瓣膜的血流动力学性能：随机PERSIST-AVR试验的1年核心实验室结果
Front Cardiovasc Med. 2022 Feb 18;9:844876. doi: 10.3389/fcvm.2022.844876. eCollection 2022.
4
Randomized controlled trial between conventional versus sutureless bioprostheses for aortic valve replacement: Impact of mini and full sternotomy access at 1-year follow-up.主动脉瓣置换术中传统瓣与免缝合生物瓣的随机对照试验：1 年随访时微创和全胸骨切开术入路的影响。
Int J Cardiol. 2022 Dec 1;368:56-61. doi: 10.1016/j.ijcard.2022.08.012. Epub 2022 Aug 6.
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Sutureless versus Stented Bioprostheses for Aortic Valve Replacement: The Randomized PERSIST-AVR Study Design.主动脉瓣置换术的无缝合与带支架生物瓣膜：随机PERSIST-AVR研究设计
Thorac Cardiovasc Surg. 2020 Mar;68(2):114-123. doi: 10.1055/s-0038-1675847. Epub 2018 Nov 29.
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Predictors of Pacemaker Insertion Post-Sutureless (Perceval) Aortic Valve Implantation.经皮无缝线（Perceval）主动脉瓣植入术后起搏器植入的预测因素。
Heart Lung Circ. 2021 Jun;30(6):917-921. doi: 10.1016/j.hlc.2020.11.004. Epub 2020 Dec 11.
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Semin Thorac Cardiovasc Surg. 2020;32(3):427-430. doi: 10.1053/j.semtcvs.2019.07.003. Epub 2019 Jul 19.
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Perioperative platelet reduction after sutureless or stented valve implantation: results from the PERSIST-AVR controlled randomized trial.经导管主动脉瓣置换术后缝合瓣环与支架瓣环的血小板减少：PERSIST-AVR 对照随机试验结果。
Eur J Cardiothorac Surg. 2021 Dec 1;60(6):1359-1365. doi: 10.1093/ejcts/ezab175.
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Letter to the Editor: Thrombocytopenia After Sutureless Aortic Valve Implantation: Does It Really Matter?致编辑的信：无缝合主动脉瓣植入术后血小板减少症：真的重要吗？
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Sutureless aortic valve replacement: a Canadian multicentre study.无缝主动脉瓣置换术：一项加拿大多中心研究。
Can J Cardiol. 2015 Jan;31(1):63-8. doi: 10.1016/j.cjca.2014.10.030. Epub 2014 Oct 31.

本文引用的文献

1
Direct comparison of rapid deployment versus sutureless aortic valve replacement: a meta-analysis.快速部署与无缝合主动脉瓣置换术的直接比较：一项荟萃分析。
J Thorac Dis. 2021 Apr;13(4):2203-2215. doi: 10.21037/jtd-20-3548.
2
Sutureless versus conventional bioprostheses for aortic valve replacement in severe symptomatic aortic valve stenosis.主动脉瓣置换术治疗严重症状性主动脉瓣狭窄：无缝合 versus 传统生物瓣。
J Thorac Cardiovasc Surg. 2021 Mar;161(3):920-932. doi: 10.1016/j.jtcvs.2020.11.162. Epub 2020 Dec 14.
3
Randomization in clinical studies.临床研究中的随机化。
Korean J Anesthesiol. 2019 Jun;72(3):221-232. doi: 10.4097/kja.19049. Epub 2019 Apr 1.
4
Rapid Deployment Versus Conventional Bioprosthetic Valve Replacement for Aortic Stenosis.主动脉瓣狭窄的快速部署与常规生物瓣置换。
J Am Coll Cardiol. 2018 Apr 3;71(13):1417-1428. doi: 10.1016/j.jacc.2018.01.065.
5
Rapid deployment or sutureless versus conventional bioprosthetic aortic valve replacement: A meta-analysis.快速部署与无缝线/常规生物瓣主动脉瓣置换术的比较：一项荟萃分析。
J Thorac Cardiovasc Surg. 2018 Jun;155(6):2402-2412.e5. doi: 10.1016/j.jtcvs.2018.01.084. Epub 2018 Feb 13.
6
Sutureless Perceval Aortic Valve Versus Conventional Stented Bioprostheses: Meta-Analysis of Postoperative and Midterm Results in Isolated Aortic Valve Replacement.经导管主动脉瓣置换术与传统主动脉瓣置换术治疗主动脉瓣狭窄的临床研究进展
J Am Heart Assoc. 2018 Feb 16;7(4):e006091. doi: 10.1161/JAHA.117.006091.
7
Aortic valve replacement in elderly with small aortic root and low body surface area; the Perceval S valve and its impact in effective orifice area.老年小主动脉根部和低体表面积患者的主动脉瓣置换；Perceval S瓣膜及其对有效瓣口面积的影响。
J Cardiothorac Surg. 2016 Apr 11;11(1):54. doi: 10.1186/s13019-016-0438-7.
8
Sutureless, rapid deployment valves and stented bioprosthesis in aortic valve replacement: recommendations of an International Expert Consensus Panel.主动脉瓣置换术中的无缝合、快速植入瓣膜及带支架生物假体：国际专家共识小组的建议
Eur J Cardiothorac Surg. 2016 Mar;49(3):709-18. doi: 10.1093/ejcts/ezv369. Epub 2015 Oct 29.
9
A comparison of conventional surgery, transcatheter aortic valve replacement, and sutureless valves in "real-world" patients with aortic stenosis and intermediate- to high-risk profile.对“真实世界”中具有中高风险特征的主动脉瓣狭窄患者进行传统手术、经导管主动脉瓣置换术和无缝合瓣膜的比较。
J Thorac Cardiovasc Surg. 2015 Dec;150(6):1570-7; discussion 1577-9. doi: 10.1016/j.jtcvs.2015.08.052. Epub 2015 Aug 24.

无缝合瓣膜——我们做到了吗？来自PERSIST-AVR试验的证据。

Sutureless valves-are we there yet? Evidence from the PERSIST-AVR trial.

作者信息

Narayan Pradeep

机构信息

Department of Cardiac Surgery, Rabindranath Tagore International Institute of Cardiac Sciences, Narayana Health, 124, EM Bypass, Mukundapur, Kolkata, 700099 India.

出版信息

Indian J Thorac Cardiovasc Surg. 2022 Jan;38(1):108-110. doi: 10.1007/s12055-021-01289-9. Epub 2021 Nov 23.

DOI:10.1007/s12055-021-01289-9
PMID:34898889
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8630234/
Abstract

Sutur eless valves have emerged as another option for implantation of a biological valve. Several benefits of sutureless valves have been reported in the literature. However, concerns have been raised over increased incidence of para-valvular leak and need for permanent pacemaker implantation. Most of the evidence has been obtained from observational and retrospective single institutional series. The Perceval Sutureless Implant Versus Standard-Aortic Valve Replacement (PERSIST-AVR) trial is the first multicentric randomized control trial to compare sutureless valves with standard bio-prosthesis. Evidence from this trial has been critically analyzed in this review.

摘要

无缝合瓣膜已成为生物瓣膜植入的另一种选择。文献中报道了无缝合瓣膜的几个优点。然而，人们对瓣周漏发生率增加以及需要植入永久性起搏器表示担忧。大多数证据来自观察性和回顾性的单机构系列研究。Perceval无缝合植入与标准主动脉瓣置换术（PERSIST-AVR）试验是第一项比较无缝合瓣膜与标准生物假体的多中心随机对照试验。本综述对该试验的证据进行了批判性分析。